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Including ethnic and cultural diversity in dementia research

Lee‐Fay Low, Annica L Barcenilla‐Wong and Bianca Brijnath
Med J Aust 2019; 211 (8): . || doi: 10.5694/mja2.50353
Published online: 21 October 2019

Australian dementia research needs increased representation of people from culturally and linguistically diverse backgrounds

Evidence‐based practice and policy must be based on the best available evidence, which should be representative of the population.1 However, the current body of dementia research does not reflect the ethnic and cultural diversity of the Australian population. Hence, people from culturally and linguistically diverse (CALD) backgrounds may receive inequitable dementia care as there is less evidence to help optimise clinical and service decisions.


  • 1 University of Sydney, Sydney, NSW
  • 2 National Ageing Research Institute, Melbourne, VIC
  • 3 Monash University, Melbourne, VIC



Acknowledgements: 

The data presented in this article were funded by the NNIDR as part of the development of the CALD Dementia Research Roadmap. Lee‐Fay Low is funded through an NHMRC Boosting Dementia Research Leadership Development Fellowship. The NNIDR were involved in conceptualising the article, but not in analysis or interpretation.

Competing interests:

Bianca Brijnath has financial relationships with government and private foundations for research and policy development specific to CALD communities and dementia.

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Responding to mandatory immigration detention: lessons for the health care community

Ryan Essex and David Isaacs
Med J Aust 2019; 211 (9): . || doi: 10.5694/mja2.50366
Published online: 14 October 2019

After 25 years of advocacy, what can the health care community learn from recent reforms of Australian immigration detention?

In February 2019, the Australian Government announced that it had removed all refugee and asylum seeker children from offshore detention in Nauru.1 Soon after, the Australian Parliament passed the Migration Amendment (Urgent Medical Treatment) Bill 2018.2 This legislation strengthens the position of doctors to recommend a transfer of an ill person to Australia for treatment from offshore detention centres in Manus Island (Papua New Guinea) and Nauru. While this has been welcome news, these developments are tempered by the fact that the government is seeking to repeal this legislation and has maintained an increasingly combative stance on these issues.


  • 1 University of Sydney, Sydney, NSW
  • 2 University of Greenwich, London, UK
  • 3 Barts Health NHS Trust, London, UK
  • 4 Children's Hospital at Westmead, Sydney, NSW


Correspondence: r.w.essex@gre.ac.uk

Competing interests:

No relevant disclosures.

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Frailty in very old critically ill patients in Australia and New Zealand: a population‐based cohort study

Jai N Darvall, Rinaldo Bellomo, Eldho Paul, Ashwin Subramaniam, John D Santamaria, Sean M Bagshaw, Sumeet Rai, Ruth E Hubbard and David Pilcher
Med J Aust 2019; 211 (7): . || doi: 10.5694/mja2.50329
Published online: 7 October 2019

Abstract

Objective: To explore associations between frailty (Clinical Frailty Scale score of 5 or more) in very old patients in intensive care units (ICUs) and their clinical outcomes (mortality, discharge destination).

Design, setting and participants: Retrospective population cohort analysis of Australian and New Zealand Intensive Care Society (ANZICS) Adult Patient Database data for all patients aged 80 years or more admitted to participating ICUs between 1 January 2017 and 31 December 2018.

Main outcome measures: Primary outcome: in‐hospital mortality; secondary outcomes: length of stay (hospital, ICU), re‐admission to ICU during the same hospital admission, discharge destination (including new chronic care or nursing home admission).

Results: Frailty status data were available for 15 613 of 45 773 patients aged 80 years or more admitted to 178 ICUs (34%); 6203 of these patients (39.7%) were deemed frail. A smaller proportion of frail than non‐frail patients were men (47% v 57%), the mean illness severity scores of frail patients were slightly higher than those of non‐frail patients, and they were more frequently admitted from the emergency department (28% v 21%) or with sepsis (12% v 7%) or respiratory complications (16% v 12%). In‐hospital mortality was higher for frail patients (17.6% v 8.2%; adjusted odds ratio [OR], 1.87 [95% CI, 1.65–2.11]). Median lengths of ICU and hospital stay were slightly longer for frail patients, and they were more frequently discharged to new nursing home or chronic care (4.9% v 2.8%; adjusted OR, 1.61 [95% CI, 1.34–1.95]).

Conclusions: Many very old critically ill patients in Australia and New Zealand are frail, and frailty is associated with considerably poorer health outcomes. Routine screening of older ICU patients for frailty could improve outcome prediction and inform intensive care and community health care planning.

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  • 1 Royal Melbourne Hospital, Melbourne, VIC
  • 2 Centre for Integrated Critical Care, University of Melbourne, Melbourne, VIC
  • 3 Austin Hospital, Melbourne, VIC
  • 4 Monash University, Melbourne, VIC
  • 5 Peninsula Health, Melbourne, VIC
  • 6 Peninsula Clinical School, Monash University, Melbourne, VIC
  • 7 St Vincent's Hospital Melbourne, Melbourne, VIC
  • 8 University of Alberta, Edmonton, AB, Canada
  • 9 ANU Medical School, Australian National University, Canberra, ACT
  • 10 Canberra Hospital, Canberra, ACT
  • 11 Centre for Health Services Research, University of Queensland, Brisbane, QLD
  • 12 The Alfred Hospital, Melbourne, VIC
  • 13 Centre for Outcome and Resource Evaluation, Australian and New Zealand Intensive Care Society, Melbourne, VIC


Correspondence: jai.darvall@mh.org.au

Acknowledgements: 

Sean Bagshaw is supported by a Canada Research Chair in Critical Care Nephrology.

Competing interests:

No relevant disclosures.

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Difficulties in knowing which critical care trial data warrant change in practice

Benjamin Reddi, Mark Finnis and Sandra Peake
Med J Aust 2019; 211 (7): . || doi: 10.5694/mja2.50331
Published online: 7 October 2019

Why is some strong evidence ignored while some weak evidence is rapidly acted upon?

Most clinicians aspire to practise evidence‐based medicine, no longer believing it acceptable to implement novel interventions simply because they “make sense” or remain untested. However, external influences, psychological factors, and misapplied statistical techniques may hinder rational decision making. Using examples from intensive care literature, we discuss why well supported therapies are not always readily adopted, while poorly supported interventions may be unduly welcomed into practice.


  • 1 Royal Adelaide Hospital, Adelaide, SA
  • 2 Queen Elizabeth Hospital, Adelaide, SA


Correspondence: Benjamin.Reddi@sa.gov.au

Competing interests:

No relevant disclosures.

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Towards gender balance in the Australian intensive care medicine workforce

Lucy J Modra and Sarah A Yong
Med J Aust 2019; 211 (7): . || doi: 10.5694/mja2.50330
Published online: 7 October 2019

Achieving gender equity in intensive care medicine requires specific interventions to attract and retain female trainees and support their progress to leadership roles

For several decades, women have comprised about half of medical graduates in Australia.1 This is yet to translate into a gender‐balanced specialty workforce. In 2016, fewer than one in five practising surgeons, cardiologists and intensivists were women.2 In recognition of this, several Colleges have developed plans to improve gender balance within their specialty.


  • 1 Austin Health, Melbourne, VIC
  • 2 Alfred Health, Melbourne, VIC
  • 3 Monash University, Melbourne, VIC


Correspondence: Lucy.MODRA@austin.org.au

Competing interests:

Lucy Modra and Sarah Yong are founding convenors of the WIN‐ANZICS Committee.

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Equity for Indigenous Australians in intensive care

Paul J Secombe, Alex Brown, Michael J Bailey and David Pilcher
Med J Aust 2019; 211 (7): . || doi: 10.5694/mja2.50339
Published online: 7 October 2019

The similarity in mortality among Indigenous and non‐Indigenous critically ill patients hides a complex story

Aboriginal and Torres Strait Islander Australians are more likely to be admitted to acute care hospitals than non‐Indigenous Australians.1 While this is widely recognised, the over‐representation of Indigenous patients in Australian intensive care units (ICUs) has been highlighted only recently.2,3 The headline finding that Indigenous Australians have an ICU admission rate that is 1.2 times the expected rate considering population representation is concerning, although not surprising, given higher Indigenous hospitalisation rates.1,2,3 It is reassuring that Indigenous patients appear to have similar in‐ICU and in‐hospital mortality.2,3 Intensivists should be justifiably proud of this mortality equivalence, but deeper analysis conveys some inconvenient truths.

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  • 1 Alice Springs Hospital, Alice Springs, NT
  • 2 Monash University, Melbourne, VIC
  • 3 South Australian Health and Medical Research Institute, Adelaide, SA
  • 4 University of South Australia, Adelaide, SA
  • 5 Alfred Health, Melbourne, VIC
  • 6 Centre for Outcome and Resource Evaluation, Australian and New Zealand Intensive Care Society, Melbourne, VIC


Correspondence: paulsecombe@bigpond.com

Competing interests:

No relevant disclosures.

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The evolving role of intensive care in health care and society

Stephen Warrillow and Raymond Raper
Med J Aust 2019; 211 (7): . || doi: 10.5694/mja2.50340
Published online: 7 October 2019
Correction(s) for this article: Erratum | Published online: 13 January 2020

Despite the evolving needs of patients and changing societal expectations, Australasian intensive care continues to provide a world leading service to patients and the broader society

With Melbourne hosting the 2019 World Congress of Intensive Care, it is timely to reflect on the nature of the speciality and consider its role within health care. The intensive care unit (ICU) can be a daunting place. For patients, families and even non‐intensive care clinicians, the complex and technically advanced environment can feel intimidating. The ICU represents a microcosm of the broader acute health care system, where the challenges of patient‐centred care, treatment, communication and resource management are encountered in a more impactful setting. The reach of intensive care is wide; current estimates from the Australian and New Zealand Intensive Care Society Centre for Outcome and Resource Evaluation suggest that Australians and New Zealanders have a 50% lifetime chance of requiring admission to an ICU.1 Intensive care interacts with every other element of acute care, serving the needs of patients, specialist units, hospitals and broader society. In its more recent history, intensive care has evolved to encompass more than just a single geographic location; it is an organised system of care that ensures delivery of timely and expert treatment to critically ill patients, increasingly extending this capability beyond the walls of the ICU itself and into many other settings.


  • 1 Austin Heath, Melbourne, VIC
  • 2 Australian and New Zealand Intensive Care Society, Melbourne, VIC
  • 3 University of Melbourne, Melbourne, VIC
  • 4 College of Intensive Care Medicine of Australia and New Zealand, Melbourne, VIC
  • 5 Royal North Shore Hospital, Sydney, NSW



Competing interests:

Stephen Warrilow is President of the Australian and New Zealand Intensive Care Society and Convenor of the 2019 World Congress of Intensive Care. Raymond Raper is President of the CICM.

  • 1. Australian and New Zealand Intensive Care Society Centre for Outcome and Resource Evaluation. Adult patient database. https://www.anzics.com.au/adult-patient-database-apd/ (viewed July 2019).
  • 2. Lichtenberg FR. The impact of biomedical innovation on longevity and health. Nordic J Health Econ 2015; 5: 45–57.
  • 3. Montgomery H, Grocott M, Mythen M. Critical care at the end of life: balancing technology with compassion and agreeing when to stop. Br J Anaesth 2017; 119 Suppl 1: i85–i89.
  • 4. Bagshaw SM, Webb SAR, Delaney A, et al. Very old patients admitted to intensive care in Australia and New Zealand: a multi‐centre cohort analysis. Crit Care 2009; 13: R45.
  • 5. Muscedere J, Waters B, Varambally A, et al. The impact of frailty on intensive care unit outcomes: a systematic review and meta‐analysis. Intensive Care Med 2017; 43: 1105–1122.
  • 6. Darvall JN, Bellomo R, Paul E, et al. Frailty in very old critically ill patients in Australia and New Zealand: a population‐based cohort study. Med J Aust 2019; 211: 318–323.
  • 7. Corke C, Leeuw E, Lo SK, George C. Predicting future intensive care demand in Australia. Crit Care Resusc. 2009; 11: 257–260.
  • 8. Melville A, Kolt G, Anderson D, et al. Admission to intensive care for palliative care or potential organ donation: demographics, circumstances, outcomes, and resource use. Crit Care Med 2017; 45: e1050–e1059.
  • 9. Hicks P, Huckson S, Fenny E, et al. The financial cost of intensive care in Australia: a multicentre registry study. Med J Aust 2019; 211: 324–325.
  • 10. Prin M, Wunsch H. International comparisons of intensive care: informing outcomes and improving standards. Curr Opin Crit Care 2012; 18: 700–706.
  • 11. Hillman KM, Chen J, Jones D. Rapid response systems. Med J Aust 2014; 201: 519–521. https://www.mja.com.au/journal/2014/201/9/rapid-response-systems
  • 12. Lasiter S, Oles SK, Mundell J, et al. Critical care follow‐up clinics: a scoping review of interventions and outcomes. Clin Nurse Spec. 2016; 30: 227–237.
  • 13. Hilton AK, Jones D, Bellomo R. Clinical review: the role of the intensivist and the rapid response team in nosocomial end‐of‐life care. Crit Care 2013; 17: 224.
  • 14. Marini JJ. Re‐tooling critical care to become a better intensivist: something old and something new. Crit Care 2015; 19 Suppl 3: S3.
  • 15. Venkatesh B, Mehta S, Angus DC, et al. Women in Intensive Care study: a preliminary assessment of international data on female representation in the ICU physician workforce, leadership and academic positions. Crit Care 2018; 22: 211.
  • 16. Modra LJ, Yong SA. Towards gender balance in the Australian intensive care medicine workforce. Med J Aust 2019; 211: 300–302.
  • 17. Warrillow S, Farley KJ, Jones D. How to improve communication quality with patients and relatives in the ICU. Minerva Anestesiol 2016; 82: 797–803.
  • 18. Anesi GL, Wagner J, Halpern SD. intensive care medicine in 2050: toward an intensive care unit without waste. Intensive Care Med 2017; 43: 554–556.
  • 19. Warrillow S, Farley K, Jones D. Ten practical strategies for effective communication with relatives of ICU patients. Intensive Care Med 2015; 41: 2173–2176.
  • 20. Bellomo R, Stow PJ, Hart GK. Why is there such a difference in outcome between Australian intensive care units and others? Curr Opin Anaesthesiol 2007; 20: 100–105.
  • 21. Peake S, Delaney A, French CJ. Evolution not revolution: the future of the randomised controlled trial in intensive care research. Med J Aust 2019; 211: 303–305.
  • 22. Haines KJ, Berney S, Warrillow S, Denehy L. Long‐term recovery following critical illness in an Australian cohort. J Intensive Care 2018; 6: 8.
  • 23. Secombe PJ, Brown A, Bailey MJ, Picher D. Diversity and equity within critical care: Indigenous Australians in intensive care. Med J Aust 2019; 211: 297–299.

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Clinically important sport‐related traumatic brain injuries in children

Nitaa Eapen, Gavin A Davis, Meredith L Borland, Natalie Phillips, Ed Oakley, Stephen Hearps, Amit Kochar, Sarah Dalton, John Cheek, Jeremy Furyk, Mark D Lyttle, Silvia Bressan, Louise Crowe, Stuart Dalziel, Emma Tavender and Franz E Babl
Med J Aust 2019; 211 (8): . || doi: 10.5694/mja2.50311
Published online: 30 September 2019

Sports participation by children and adolescents is generally high in Australia and New Zealand,1,2 and many children sustain head injuries of varying severity during such activities. Concussion has received increasing attention, but less is known about the risk of severe acute intracranial injuries in children with sports‐related head injuries.3

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  • 1 Royal Children's Hospital, Melbourne, VIC
  • 2 Murdoch Children's Research Institute, Melbourne, VIC
  • 3 University of Melbourne, Melbourne, VIC
  • 4 Perth Children's Hospital, Perth, WA
  • 5 University of Western Australia, Perth, WA
  • 6 Queensland Children's Hospital, Brisbane, QLD
  • 7 Children's Health Research Centre, University of Queensland, Brisbane, QLD
  • 8 Women's and Children's Hospital, Adelaide, SA
  • 9 Children's Hospital at Westmead, Sydney, NSW
  • 10 The Townsville Hospital, Townsville, QLD
  • 11 Bristol Royal Hospital for Children, Bristol, United Kingdom
  • 12 University of Padova, Padova, Italy
  • 13 Starship Children's Health, Auckland, New Zealand
  • 14 University of Auckland, Auckland, New Zealand


Correspondence: franz.babl@rch.org.au

Acknowledgements: 

The study was funded by grants from the National Health and Medical Research Council (NHMRC; project grant GNT1046727, Centre of Research Excellence for Paediatric Emergency Medicine GNT1058560); the Murdoch Children's Research Institute, Melbourne; the Emergency Medicine Foundation, Brisbane (EMPJ‐11162); Perpetual Philanthropic Services (2012/1140); Auckland Medical Research Foundation (3112011) and the A + Trust (Auckland District Health Board); WA Health Targeted Research Funds 2013; and the Townsville Hospital and Health Service Private Practice Research and Education Trust Fund; and was supported by the Victorian Government Infrastructure Support Program. Franz Babl was partly funded by an NHMRC Practitioner Fellowship and a Melbourne Campus Clinician Scientist fellowship. Stuart Dalziel was partly funded by the Health Research Council of New Zealand (HRC13/556).

Competing interests:

No relevant disclosures.

  • 1. Australian Bureau of Statistics. 4156.0. Sports and physical recreation: a statistical overview, 2012. Dec 2012. http://www.abs.gov.au/ausstats/abs@.nsf/Products/76DF25542EE96D12CA257AD9000E2685?opendocument (viewed Sept 2018).
  • 2. Brocklesby J, McCarty G., Active NZ. Main report — the New Zealand Participation Survey 2017. Wellington: Sport New Zealand, 2018. https://sportnz.org.nz/assets/Uploads/Main-Report.pdf (viewed Sept 2018).
  • 3. Davies GA, Anderson V, Babl FE, et al. What is the difference in concussion management in children as compared with adults? A systematic review. Br J Sports Med 2017; 51: 949–957.
  • 4. Babl FE, Borland ML, Phillips N, et al. Paediatric Research in Emergency Departments International Collaborative (PREDICT). Accuracy of PECARN, CATCH and CHALICE head injury decision rules in children: a prospective cohort study. Lancet 2017; 389: 2393–2402.
  • 5. Kuppermann N, Holmes JF, Dayan PS, et al. Pediatric Emergency Care Applied Research Network (PECARN). Identification of children at very low risk of clinically‐important traumatic brain injuries after head trauma: a prospective cohort study. Lancet 2009; 374: 1160–1170.

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Health care for older people in rural and remote Australia: challenges for service provision

Fergus W Gardiner, Alice M Richardson, Lara Bishop, Abby Harwood, Elli Gardiner, Lauren Gale, Narcissus Teoh, Robyn M Lucas and Martin Laverty
Med J Aust 2019; 211 (8): . || doi: 10.5694/mja2.50277
Published online: 30 September 2019

Many Australians living in rural and remote areas of Australia need to travel hundreds of kilometres for health care service, or to wait for health service providers, such as the Royal Flying Doctor Service (RFDS), to visit them. The levels of acute and subacute hospital services in rural and remote areas are reported to be inadequate,1 as is, to a lesser extent, access to aged care services.2 The need to travel long distances is a major barrier for people in remote locations, particularly older people, seeking health care.

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  • 1 Royal Flying Doctor Service of Australia, Canberra, ACT
  • 2 National Centre for Epidemiology and Population Health, Research School of Population Health, Australian National University, Canberra, ACT
  • 3 College of Health and Medicine, Australian National University, Canberra, ACT
  • 4 Royal Flying Doctor Service, Queensland Section, Cairns, QLD


Correspondence: fergus.gardiner@rfds.org.au

Competing interests:

No relevant disclosures.

  • 1. Davis J, Morgans A, Stewart J. Developing an Australian health and aged care research agenda: a systematic review of evidence at the subacute interface. Aust Health Rev 2016; 40: 420–427.
  • 2. van Gaans D, Dent E. Issues of accessibility to health services by older Australians: a review. Public Health Rev 2018; 39: 20.
  • 3. Australian Institute of Health and Welfare. Older Australia at a glance (AGE 87). Canberra: AIHW, 2018. https://www.aihw.gov.au/reports/older-people/older-australia-at-a-glance (viewed June 2019).
  • 4. Gardiner FW, Gale L, Bishop L, Laverty M. Healthy ageing in rural and remote Australia: challenges and gaps in service provision to overcome. Canberra: The Royal Flying Doctor Service of Australia, 2018. https://www.flyingdoctor.org.au/assets/documents/RN069_Healthy_Ageing_Report_D3.pdf (viewed June 2019).
  • 5. Cui X, Zhou X, Ma LL, et al. A nurse‐lead structured education program improves self‐management skills and reduces hospital readmissions in patients with chronic heart failure: a randomized and controlled trial. Rural Remote Health 2019; 19: 5270.

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First reported case of extensively drug‐resistant typhoid in Australia

Annaleise Howard‐Jones, Alison M Kesson, Alexander C Outhred and Philip N Britton
Med J Aust 2019; 211 (6): . || doi: 10.5694/mja2.50316
Published online: 16 September 2019

To the Editor: The period from January to March marks the peak season for travellers returning to Australia, and typhoid is a key illness of concern. Since 2016, an extensively drug‐resistant (XDR) typhoid clade has emerged in Pakistan, showing resistance to all first‐line agents.1,2 Over the past 2 years, seven cases have been reported in returned travellers — mostly children — from Pakistan to England, Germany and the United States.1,3,4


  • 1 Children's Hospital at Westmead, Sydney, NSW
  • 2 University of Sydney, Sydney, NSW



Competing interests:

No relevant disclosures.

  • 1. Klemm EJ, Shakoor S, Page AJ, et al. Emergence of an extensively drug‐resistant Salmonella enterica serovar Typhi clone harboring a promiscuous plasmid encoding resistance to fluoroquinolones and third‐generation cephalosporins. MBio 2018; 9: pii e00105‐18.
  • 2. World Health Organization. Disease outbreaks in Eastern Mediterranean Region (EMR), January to December 2018. WHO EMRO Weekly Epidemiology Monitor 2018; 11: 1. http://applications.emro.who.int/docs/epi/2018/Epi_Monitor_2018_11_52.pdf?ua=1 (viewed July 2019).
  • 3. Chatham‐Stephens K, Medalla F, Hughes M, et al. Emergence of extensively drug‐resistant Salmonella Typhi infections among travelers to or from Pakistan — United States, 2016–2018. MMWR Morb Mortal Wkly Rep 2019; 68: 11–13.
  • 4. Kleine CE, Schlabe S, Hischebeth GTR, Molitor E, Pfeifer Y, Wasmuth JC, et al. Successful therapy of a multidrug‐resistant extended‐spectrum β‐lactamase‐producing and fluoroquinolone‐resistant Salmonella enterica Subspecies enterica serovar Typhi infection using combination therapy of meropenem and fosfomycin. Clin Infect Dis 2017; 65: 1754–1756.
  • 5. Khatami A, Khan F, Macartney KK. Enteric fever in children in Western Sydney, Australia, 2003–2015. Pediatr Infect Dis J 2017; 36: 1124–1128.

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