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Collaborative systems are required to combat the rising challenge of antimicrobial resistance in health care facilities and the community
These germs of disease have taken toll of humanity since the beginning of things—taken toll of our prehuman ancestors since life began here. But by virtue of this natural selection of our kind we have developed resisting power; to no germs do we succumb without a struggle …
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Deborah Williamson is supported by a National Health and Medical Research Council (NHMRC) Early Career Fellowship (GNT1123854). Benjamin Howden is supported by an NHMRC Practitioner Fellowship (GNT1105905).
David Patterson has received research grants or honoraria for participation in advisory boards from Shionogi, MSD, Pfizer, Achaogen, Entasis Therapeutics and Accelerate Diagnostics.
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We thank James McFadyen, Indi Rasaratnam, Juan Aw and Shom Bhattacharjee of Alfred Health for contributing to the content and review of this article.
Huyen Tran has received grants from Bayer Health and Pfizer and speaker honoraria from Bayer Health and Boehringer Ingelheim.
Introduction: Representatives appointed by relevant Australian medical societies used a systematic approach for adaptation of guidelines (ADAPTE) to formulate clinical consensus recommendations on assessment and management of bone health in women with oestrogen receptor‐positive early breast cancer receiving endocrine therapy. The current evidence suggests that women receiving adjuvant aromatase inhibitors and pre‐menopausal woman treated with tamoxifen have accelerated bone loss and that women receiving adjuvant aromatase inhibitors have increased fracture risk. Both bisphosphonates and denosumab prevent bone loss; additionally, denosumab has proven anti‐fracture benefit in post‐menopausal women receiving aromatase inhibitors for hormone receptor‐positive breast cancer.
Main recommendations:
Changes in management as result of the position statement:
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We thank the Endocrine Society of Australia Council (chair Warrick Inder); the Australian and New Zealand Bone and Mineral Society (ANZBMS) Council (president Emma Duncan during the writing and reviewing of this statement); the ANZBMS Therapeutics Committee (chair Richard Prince); the ANZBMS Densitometry Committee (chair Nicholas Pocock); Australasian Menopause Society board members, executive director and past presidents Jane Elliott and Anna Fenton; and the Clinical Oncology Society of Australia Council (chair Phyllis Butow) for their support, expert reviews and valuable contributions to this statement.
Mathis Grossmann has received speaker honoraria and conference support from Besins and Amgen Australia, has been an advisory board member for Otsuka, and has received research support from Bayer, Novartis, Weight Watchers and Eli Lilly. Sabashini Ramchand has received speaker honoraria from Counterpart (breast cancer). Frances Milat has received speaker honoraria and conference support from Novo Nordisk. Amanda Vincent has received speaker honoraria, conference support and research support from Amgen Australia, and has been a Cancer Australia working party member on management of menopause in women with breast cancer (honorary position). Elgene Lim has received speaker honoraria and conference support from Roche, Novartis and Amgen Australia, has been an advisory board member for TEVA, Novartis, Roche, Pfizer Oncology and Bayer, and has received research support from Bayer and Novartis. Mark Kotowicz has received speaker honoraria and conference support from Amgen Australia and Eli Lilly, has been an advisory board member for Amgen Australia and Eli Lilly, and has received research support from Amgen Australia. Helena Teede has received speaker honoraria and conference support from Novo Nordisk, has been an advisory board member for Diabetes Australia Victoria (honorary position), has received research support from Janssen Cilag, and is director of the Epworth Sleep Centre, Melbourne.
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No relevant disclosures.
Introduction: In Australia, mental health conditions (MHCs) arising from workplace factors are a leading cause of long term work incapacity and absenteeism. While most patients are treated in general practice, general practitioners report several challenges associated with diagnosing and managing workplace MHCs.
This guideline, approved by the National Health and Medical Research Council and endorsed by the Royal Australian College of General Practitioners and the Australian College of Rural and Remote Medicine, is the first internationally to address the clinical complexities associated with diagnosing and managing work‐related MHCs in general practice.
Main recommendations: Our 11 evidence‐based recommendations and 19 consensus‐based statements aim to assist GPs with:
Changes in management as result of the guideline: This guideline will enhance care and improve health outcomes by encouraging:
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© 2019 The Authors. Medical Journal of Australia published on behalf of AMPCo Pty Ltd
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
The development of this guideline was supported by the Australian Government Department of Jobs and Small Business and Comcare, the Office of Industrial Relations — Queensland Government, the State Insurance Regulatory Authority (NSW), ReturntoWorkSA, WorkCover WA and the Institute of Safety, Compensation and Recovery Research. The development of the final recommendations has not been influenced by the views or interests of the funding bodies.
The online Supporting Information includes the declaration of competing interests.
Objective: To estimate the prevalence of polypharmacy among Australians aged 70 years or more, 2006–2017.
Design, setting and participants: Analysis of a random 10% sample of Pharmaceutical Benefits Scheme (PBS) data for people aged 70 or more who were dispensed PBS‐listed medicines between 1 January 2006 and 31 December 2017.
Main outcome measures: Prevalence of continuous polypharmacy (five or more unique medicines dispensed during both 1 April – 30 June and 1 October – 31 December in a calendar year) among older Australians, and the estimated number of people affected in 2017; changes in prevalence of continuous polypharmacy among older concessional beneficiaries, 2006–2017.
Results: In 2017, 36.1% of older Australians were affected by continuous polypharmacy, or an estimated 935 240 people. Rates of polypharmacy were higher among women than men (36.6% v 35.4%) and were highest among those aged 80–84 years (43.9%) or 85–89 years (46.0%). The prevalence of polypharmacy among PBS concessional beneficiaries aged 70 or more increased by 9% during 2006–2017 (from 33.2% to 36.2%), but the number of people affected increased by 52% (from 543 950 to 828 950).
Conclusions: The prevalence of polypharmacy among older Australians is relatively high, affecting almost one million older people, and the number is increasing as the population ages. Our estimates are probably low, as we could not take over‐the‐counter or complementary medicines or private prescriptions into account. Polypharmacy can be appropriate, but there is substantial evidence for its potential harm and the importance of rationalising unnecessary medicines, particularly in older people.
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This investigation was supported by the National Health and Medical Research Council (NHMRC) Centre for Research Excellence in Medicines and Ageing (CREMA; 1060407). Michael Falster and Amy Page are supported by NHMRC Early Career Fellowships (1139133, 1156892). We thank the Department of Human Services for providing the data for our analysis.
Sallie Pearson and Christopher Etherton‐Beer are members of the Drug Utilisation Sub‐Committee of the Pharmaceutical Benefits Advisory Committee. The views expressed in this article do not represent those of the Committee.
Medicare criteria may hinder timely diagnosis and treatment of patients
This issue of the MJA includes a timely analysis of the value of questionnaires in screening for obstructive sleep apnoea (OSA) in primary care.1 It has particular relevance for contemporary Australian health care, given the new Medicare provisions for pre‐test OSA screening. The study by Senaratna and colleagues is valuable for health care providers and administrators because it illustrates the limitations of questionnaires for screening, let alone for diagnosing, OSA.
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No relevant disclosures.
The strengths of primary care should be harnessed to address complexities of the ageing population
The Australian Institute for Health and Welfare estimates that by 2057 there will be 8.8 million Australians aged 65 years and over, representing 22% of the population. This is an increase from 3.8 million (15% of the population) in 2017.1 The Institute also found that although around 70% self‐assess their health as being good, very good or excellent, around 20% overall experience severe or profound core activity limitation. This applies to around 50% by 85 years of age.
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© 2019 The Authors. Medical Journal of Australia published by AMPCo Pty Ltd
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Dimity Pond has served on the advisory board for Nutricia, and has received funding from a range of primary care organisations for delivery of dementia education.
Training doctors through regional teaching health service networks may help deliver sustainable high quality health care closer to home for rural Australians
The principle of universal health coverage is passionately espoused by the global community and linked to developing the right workforce, with the right skills, in the right place.1,2 But Australia has already achieved this through Medicare and state‐funded hospitals which can deliver higher than average life expectancy and minimise maternal and neonatal morbidity. Right? Wrong!
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Paul Worley is the National Rural Health Commissioner, and Belinda O'Sullivan and Rose Ellis are employed in the Office of the National Rural Health Commissioner. The National Rural Health Commissioner is an independent statutory officer. The views expressed in this article are those of the authors and do not represent an official position of the Commonwealth Department of Health or the Australian Government.
Abstract
Introduction: Rising demand for gender‐affirming hormone therapy mandates a need for more formalised care of transgender and gender diverse (TGD) individuals in Australia. Estimates suggest that 0.1–2.0% of the population are TGD, yet medical education in transgender health is lacking. We aim to provide general practitioners, physicians and other medical professionals with specific Australian recommendations for the hormonal and related management of adult TGD individuals.
Main recommendations:
Changes in management as result of this position statement: Gender‐affirming hormone therapy is effective and, in the short term, relatively safe with appropriate monitoring. Further research is needed to guide clinical care and understand long term effects of hormonal therapies. We provide the first guidelines for medical practitioners to aid the provision of gender‐affirming care for Australian adult TGD individuals.