An article in the 20 September issue of the Journal that suggested circumcision of infant boys could be considered a "surgical vaccine" against future sexually transmitted HIV has attracted strong criticism from many of our readers (MJA 2011; 194: 97-101)
To the Editor: In a recent editorial, Cooper and colleagues recommend increasing infant circumcision to combat increasing rates of heterosexual transmission of HIV infection, and contend that the major obstacle to increasing male circumcision in Australia is a Royal Australasian College of Physicians (RACP) policy.1
The full article is accessible to AMA members and paid subscribers. Login to read more or purchase a subscription now.
Please note: institutional and Research4Life access to the MJA is now provided through Wiley Online Library.
- 1. Cooper DA, Wodak AD, Morris BJ. The case for boosting infant male circumcision in the face of rising heterosexual transmission of HIV [editorial]. Med J Aust 2010; 193: 318-319. <MJA full text>
- 2. Royal Australasian College of Physicians. Circumcision of infant males. Sydney: RACP, 2010. http://www.racp.edu.au/index.cfm?objectid=65118B16-F145-8B74-236C86100E4E3E8E (accessed Dec 2010).
- 3. Siegfried N, Muller M, Deeks JJ, Volmink J. Male circumcision for prevention of heterosexual acquisition of HIV in men. Cochrane Database Syst Rev 2009; (2): CD003362.
- 4. Templeton DJ, Jin F, Mao L, et al. Circumcision and risk of HIV infection in Australian homosexual men. AIDS 2009; 23: 2347-2351.
- 5. Templeton DJ, Jin F, Prestage GP, et al. Circumcision and risk of sexually transmissible infections in a community-based cohort of HIV-negative homosexual men in Sydney, Australia. J Infect Dis 2009; 200: 1813-1819.
- 6. Wawer MJ, Makumbi F, Kigozi G, et al. Circumcision in HIV-infected men and its effect on HIV transmission to female partners in Rakai, Uganda: a randomised controlled trial. Lancet 2009; 374: 229-237.
- 7. Royal Dutch Medical Association. Non-therapeutic circumcision of male minors. Utrecht: KNMG, 2010. http://knmg.artsennet.nl/web/file?uuid=579e836d-ea83-410f-9889-feb7eda87cd5&owner=a8a9ce0e-f42b-47a5-960e-be08025b7b04&contentid=77976&elementid=771754 (accessed Dec 2010).
- 8. Cooper DA, Wodak AD, Morris BJ. The case for boosting infant male circumcision in the face of rising heterosexual transmission of HIV [editorial]. Med J Aust 2010; 193: 318-319. <MJA full text>
- 9. Mor Z, Kent CK, Kohn RP, Klausner JD. Declining rates in male circumcision amidst increasing evidence of its public health benefit. PLoS ONE 2007; 2: e861.
- 10. Centers for Disease Control and Prevention. Racial/ethnic disparities in diagnoses of HIV/AIDS — 33 states, 2001–2005. MMWR Morb Mortal Wkly Rep 2007; 56: 189-193.
- 11. Sorrells ML, Snyder JL, Reiss MD, et al. Fine-touch pressure thresholds in the adult penis. BJU Int 2007; 99: 864-869.
- 12. Bollinger D. Lost boys: an estimate of US circumcision-related infant deaths. Thymos 2010; 4: 78-90.
- 13. Secretary, Department of Health and Community Services v JWB and SMB (Marion’s case) (1992) 175 CLR 218, FC 92/010.
- 14. Schoen EJ, Colby CJ, To TT. Cost analysis of neonatal circumcision in a large health maintenance organization. J Urol 2006; 175: 1111-1115.
- 15. McAllister RG, Travis JW, Bollinger D, et al. The cost to circumcise Africa. Int J Men’s Health 2008; 7: 307-316.
- 16. Royal Australasian College of Physicians. Circumcision of infant males. Sydney: RACP, 2010. http://www.racp.edu.au/index.cfm?objectid=65118B16-F145-8B74-236C86100E4E3E8E (accessed Dec 2010).
- 17. Llewellyn DJ. The circumcision lobby. The 11th International Symposium on Circumcision, Genital Integrity, and Human Rights. Genital Autonomy. Program and Syllabus of Abstracts; 2010 Jul 29–31; University of California, Berkeley. www.nocirc.org/symposia/eleventh/symposium2010web.pdf (accessed Dec 2010).
- 18. Royal Dutch Medical Association. Non-therapeutic circumcision of male minors. Utrecht: KNMG, 2010. http://knmg.artsennet.nl/web/file?uuid=579e836d-ea83-410f-9889-feb7eda87cd5&owner=a8a9ce0e-f42b-47a5-960e-be08025b7b04&contentid=77976&elementid=771754 (accessed Dec 2010).
- 19. Cooper DA, Wodak AD, Morris BJ. The case for boosting infant male circumcision in the face of rising heterosexual transmission of HIV [editorial]. Med J Aust 2010; 193: 318-319. <MJA full text>
- 20. Doyle SM, Kahn JG, Hosang N, et al. The impact of male circumcision on HIV transmission. J Urol 2010; 183: 21-26.
- 21. Grierson J, Power J, Croy S, et al. HIV futures six: making positive lives count. Melbourne: La Trobe University, 2009.
- 22. National Centre in HIV Epidemiology and Clinical Research. HIV/AIDS, viral hepatitis and sexually transmissible infections in Australia: annual surveillance report 2009. http://www.nchecr.unsw.edu.au/NCHECRweb.nsf/resources/SurvReports_3/$file/ASR2009-updated-2.pdf (accessed Sep 2010).
- 23. Millett GA, Flores SA, Marks G, et al. Circumcision status and risk of HIV and sexually transmitted infections among men who have sex with men: a meta-analysis. JAMA 2008; 300: 1674-1684.
- 24. Cooper DA, Wodak AD, Morris BJ. The case for boosting infant male circumcision in the face of rising heterosexual transmission of HIV [editorial]. Med J Aust 2010; 193: 318-319. <MJA full text>
- 25. Smith DK, Taylor A, Kilmarx PH, et al. Male circumcision in the United States for the prevention of HIV infection and other adverse health outcomes: a report from a CDC consultation. Public Health Rep 2010; 125 Suppl 1: 72-82.
- 26. Centers for Disease Control and Prevention. Male circumcision and risk for HIV transmission and other health conditions: implications for the United States [CDC HIV/AIDS science facts]. Atlanta: CDC, 2008. http://www.cdc.gov/hiv/resources/factsheets/circumcision.htm (accessed Oct 2010).
- 27. Morris BJ. Why circumcision is a biomedical imperative for the 21st century. Bioessays 2007; 29: 1147-1158.
- 28. Cooper DA, Wodak AD, Morris BJ. The case for boosting infant male circumcision in the face of rising heterosexual transmission of HIV [editorial]. Med J Aust 2010; 193: 318-319. <MJA full text>
- 29. Wawer MJ, Makumbi F, Kigozi G, et al. Circumcision in HIV-infected men and its effect on HIV transmission to female partners in Rakai, Uganda: a randomised controlled trial. Lancet 2009; 374: 229-237.
- 30. Boyle GJ, Svoboda JS, Price CP, Turner JN. Circumcision of healthy boys: criminal assault? J Law Med 2000; 7: 301-310.
- 31. UNAIDS. Country factsheets. Geneva: UNAIDS, 2010. http://cfs.unaids.org/ (accessed Dec 2010).
- 32. National Centre in HIV Epidemiology and Clinical Research. HIV/AIDS, viral hepatitis and sexually transmissible infections in Australia: annual surveillance report 2009. Sydney: NCHECR, 2009.
- 33. Richters J, Smith AMA, de Visser RO, et al. Circumcision in Australia: prevalence and effects on sexual health. Int J STD AIDS 2006; 17: 547-554.
- 34. Millett GA, Flores SA, Marks G, et al. Circumcision status and risk of HIV and sexually transmitted infections among men who have sex with men: a meta-analysis. JAMA 2008; 300: 1674-1684.
- 35. Boyle GJ, Goldman R, Svoboda JS, Fernandez E. Male circumcision: pain, trauma and psychosexual sequelae. J Health Psych 2002; 7: 329-343.
- 36. Cooper DA, Wodak AD, Morris BJ. The case for boosting infant male circumcision in the face of rising heterosexual transmission of HIV [editorial]. Med J Aust 2010; 193: 318-319. <MJA full text>
- 37. Green LW, McAlister RG, Peterson KW, Travis JW. Male circumcision is not the surgical vaccine we have been waiting for. Futur HIV Ther 2008; 2: 193-199.
- 38. Myers A, Myers JE. Rolling out male circumcision as a mass HIV/AIDS intervention seems neither justified nor practicable [editorial]. S Afr Med J 2008; 98: 781-782.
- 39. Siegfried N, Muller M, Deeks JJ, Volmink J. Male circumcision for prevention of heterosexual acquisition of HIV in men. Cochrane Database Syst Rev 2009; (2): CD003362.
- 40. Perera CL, Bridgewater FHG, Thavaneswaran P, Maddern GJ. Safety and efficacy of nontherapeutic male circumcision: a systematic review. Ann Fam Med 2010; 8: 64-72.
- 41. Royal Australasian College of Physicians. Circumcision of infant males. Sydney: RACP, 2010. http://www.racp.edu.au/index.cfm?objectid=65118B16-F145-8B74-236C86100E4E3E8E (accessed Dec 2010).
- 42. Cooper DA, Wodak AD, Morris BJ. The case for boosting infant male circumcision in the face of rising heterosexual transmission of HIV [editorial]. Med J Aust 2010; 193: 318-319. <MJA full text>
- 43. Zoossmann-Diskin A, Blustein R. Challenges to circumcision in Israel. In: Denniston GC, Mansfield Hodges F, Milos MF, editors. Male and female circumcision: medical, legal and ethical considerations in pediatric practice. New York: Kluwer Academic/Plenum Publishers, 1999: 343-350.
- 44. Taylor JR, Lockwood AP, Taylor AJ. The prepuce: specialized mucosa of the penis and its loss to circumcision. Br J Urol 1996; 77: 291-295.
- 45. Fleiss PM, Hodges FM, Van Howe RS. Immunological functions of the human prepuce. Sex Transm Infect 1998; 74: 364-367.
- 46. Cold CJ, Taylor JR. The prepuce. Br J Urol 1999; 83 Suppl 1: 41.
- 47. Cooper DA, Wodak AD, Morris BJ. The case for boosting infant male circumcision in the face of rising heterosexual transmission of HIV [editorial]. Med J Aust 2010; 193: 318-319. <MJA full text>
- 48. Schoen EJ. Circumcision as a lifetime vaccination with many benefits. J Men’s Hlth Gender 2007; 4: 306-311.
- 49. Morris BJ. Why circumcision is a biomedical imperative for the 21st century. Bioessays 2007; 29: 1147-1158.
- 50. Ben KL, Xu JC, Lu L, et al. [Male circumcision is an effective “surgical vaccine” for HIV prevention and reproductive health] [Chinese]. Zhonghua Nan Ke Xue 2009; 15: 395-402.
- 51. Tobian AA, Gray RH, Quinn TC. Male circumcision for the prevention of acquisition and transmission of sexually transmitted infections: the case for neonatal circumcision. Arch Pediatr Adolesc Med 2010; 164: 78-84.
- 52. Warner L, Ghanem KG, Newman DR, et al. Male circumcision and risk of HIV infection among heterosexual African American men attending Baltimore sexually transmitted disease clinics. J Infect Dis 2009; 199: 59-65.
- 53. Sansom SL, Prabhu VS, Hutchinson AB, et al. Cost-effectiveness of newborn circumcision in reducing lifetime HIV risk among US males PLoS One 2010; 5: e8723.
- 54. Weiss HA, Hankins CA, Dickson K. Male circumcision and risk of HIV infection in women: a systematic review and meta-analysis. Lancet Infect Dis 2009; 9: 669-677.
- 55. Hallett TB, Alsallaq RA, Baeten JM, et al. Will circumcision provide even more protection from HIV to women and men? New estimates of the population impact of circumcision interventions. Sex Transm Infect 2010; Oct 21 [Epub ahead of print].
- 56. Templeton DJ, Jin F, Mao L, et al. Circumcision and risk of HIV infection in Australian homosexual men. AIDS 2009; 23: 2347-2351.
- 57. Krieger JN, Mehta SD, Bailey RC, et al. Adult male circumcision: effects on sexual function and sexual satisfaction in Kisumu, Kenya. J Sex Med 2008; 5: 2610-2622.
- 58. Wamai RG, Weiss HA, Hankins C, et al. Male circumcision is an efficacious, lasting and cost-effective strategy for combating HIV in high-prevalence AIDS epidemics. Future HIV Ther 2008; 2: 399-405.
- 59. Slaymaker E. A critique of international indicators of sexual risk behaviour. Sex Transm Infect 2004; 80 Suppl 2: ii13-ii21.
- 60. Russell T. Non-circumcision a legal risk. Aust Doctor 1996; Sep 20: 57.
- 61. National Centre in HIV Epidemiology and Clinical Research. HIV/AIDS, viral hepatitis and sexually transmissible infections in Australia: annual surveillance report 2009. http://www.nchecr.unsw.edu.au/NCHECRweb.nsf/resources/SurvReports_3/$file/ASR2009-updated-2.pdf (accessed Dec 2010).
We thank John Allegrante, Mailman School of Public Health, Columbia University; Rouma Bankolé, University Hospital Cancer Research Center, Abidjan, Ivory Coast; Michel Garenne, Pasteur Institute, Paris; David Jones, University of Vermont; Julius Kyambi, University of Nairobi; Maria Isabel Loureiro, National School of Public Health, Lisbon; Donald Morisky, UCLA School of Public Health; Kyle Pruett, Yale School of Medicine; Timothy Quinlan, University of KwaZulu-Natal, Durban, South Africa; Daniel Sidler, Tygerberg Children’s Hospital, South Africa; Lukong Suiye, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria; and Lauraine Vivian, Groote Schuur Hospital, University of Cape Town — a few of the many professionals who have questioned the value of non-therapeutic male circumcision — for their encouragement and support.