Connect
MJA
MJA

Convulsions associated with an overdose of St John’s wort

Dharshi C Karalapillai and Rinaldo Bellomo
Med J Aust 2007; 186 (4): . || doi: 10.5694/j.1326-5377.2007.tb00867.x
Published online: 19 February 2007

To the Editor: St John’s wort (SJW) (Hypericum perforatum) is a natural medicine commonly used for treating depression. We recently encountered a case of an overdose of SJW leading to serious manifestations in the patient.


  • Intensive Care Department, Austin and Repatriation Hospital, Melbourne, VIC.


Correspondence: dharshik31@hotmail.com

  • 1. Linde K, Berner M, Egger M, Mulrow C. St Johns wort for depression: a meta-analysis of randomized controlled trials. Br J Psychiatry 2005; 186: 99-107.
  • 2. Knuppel L, Linde K. Adverse effects of St Johns wort: a systematic review. J Clin Psychiatry 2004; 65: 1470-1479.
  • 3. Fugh-Berman A. Herb–drug interactions. Lancet 2000; 355: 134-138.
  • 4. Haller CA, Meier KH, Olson KR. Seizures reported in association with the use of dietary supplements. Clin Toxicol (Phila) 2005; 43: 23-30.
  • 5. Parker V, Wong AHC, Boon HS, Seeman MV. Adverse reactions to St Johns wort. Can J Psychiatry 2001; 46: 77-79.

Author

remove_circle_outline Delete Author
add_circle_outline Add Author

Comment
Do you have any competing interests to declare? *

I/we agree to assign copyright to the Medical Journal of Australia and agree to the Conditions of publication *
I/we agree to the Terms of use of the Medical Journal of Australia *
Email me when people comment on this article

Online responses are no longer available. Please refer to our instructions for authors page for more information.