The use of biological agents as weapons of war is not new. In the 14th-century siege of Kaffa, on the Black Sea, the attacking Tartars catapulted bodies of plague victims at the defending Genoese, who contracted the disease and abandoned the city. Over the past century, many countries have developed the capacity to use biological agents to produce casualties in humans and domestic animals and to damage crops and environmental systems. Some biowarfare programs are known to have continued despite the adoption by 144 countries of the 1972 Biological Weapons Convention, which prohibited development or acquisition of such weapons.
The full article is accessible to AMA members and paid subscribers. Login to read more or purchase a subscription now.
Please note: institutional and Research4Life access to the MJA is now provided through Wiley Online Library.
- 1 Infection Management Services, Princess Alexandra Hospital, Brisbane, QLD.
- 2 Victorian Infectious Diseases Service, Royal Melbourne Hospital, Melbourne, VIC.
- 3 GlaxoSmithKline Biologicals, Melbourne, VIC.
- 4 John Curtin School of Medical Research, Australian National University, Canberra, ACT.
- 1. Fenner F, Henderson DA, Arita I. Smallpox and its eradication. Geneva: World Health Organization, 1988.
- 2. Gani R, Leach S. Transmission potential of smallpox in contemporary populations. Nature 2001; 414: 748-751.
- 3. Wehrle FF, Poach J, Richter KM, et al. An airborne outbreak of smallpox in a German hospital and its significance with respect to other recent outbreaks in Europe. Bull WHO 1970; 43: 669-679.
- 4. Henderson DA, Inglesby TV, Bartlett JG, et al. Smallpox as a biological weapon. Medical and public health management. JAMA 1999; 281: 2127-2137.
- 5. Alibek K, Handelman S. Biohazard. New York: Random House, 1999.
- 6. Smallwood RA, Merianos A, Mathews JD. Bioterrorism in Australia. Med J Aust 2002; 176: 251-253.
- 7. Paterson DL, King M, Boyle R, et al. Severe botulism after eating home-preserved asparagus. Med J Aust 1992; 157: 269-270.
- 8. Working Group on Civilian Bio-Defense. Botulinum toxin as a biological weapon: medical and public health management. JAMA 2001; 285: 1059-1170.
- 9. Hatheway CL. Botulism: The present status of the disease. Curr Top Microbiol Immunol 1995; 195: 55-75.