A 66‐year‐old man presented to a tertiary emergency department following a fall. He had a 6‐month history of agitation, personality change, progressive cognitive impairment, dysarthria, dysphagia and recurrent falls. On examination, there was proximal muscle wasting and weakness, brisk reflexes and an upgoing plantar reflex on the left foot. Cranial nerve examination was normal.
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- 1. Berger JR, Aksamit AJ, Clifford DB, et al. PML diagnostic criteria: consensus statement from the AAN neuroinfectious disease section. Neurology 2013; 80: 1430–1438.
- 2. Pavlovic D, Patera AC, Nyberg F, et al. Progressive multifocal leukoencephalopathy: current treatment options and future perspectives. Therap Adv Neurol Disord 2015; 8: 255–273.
- 3. Bennett KM, Storrar N, Johnson P, Fernandes PM. Progressive multifocal leukoencephalopathy (PML) following autologous peripheral blood stem cell transplantation for multiple myeloma. Clin Case Rep 2020; 8: 938–943.
- 4. Akiyama M, Takahashi T, Nomura S, et al. Progressive multifocal leukoencephalopathy in patient with multiple myeloma. Int J Hematol 2010; 92: 186.
- 5. Cortese, I, Muranski P, Enose‐Akahata Y, et al. Pembrolizumab treatment for progressive multifocal leukoencephalopathy. N Engl J Med 2019; 380: 1597–1605.
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