Managing patients with acute chest pain should include opportunistic discussion of strategies for preventing coronary artery disease
Chest pain is a frequent symptom in patients presenting to emergency departments. Assessing blood troponins is critical for rapid diagnosis,1 and guidelines clearly outline therapeutic strategies for patients diagnosed with acute myocardial infarction.2 However, evidence for guiding further management when myocardial infarction has been excluded — that is, for most people who present with chest pain — is less definite. As the risk of myocardial infarction or death within 12 months for such patients is 2–9%,1 accurate risk estimation and further preventive treatment are important. The 2020 European Society of Cardiology guidelines for non‐ST‐elevation myocardial infarction recommend non‐invasive cardiac imaging in patients without acute coronary syndrome only when coronary artery disease is nevertheless suspected.3 Further evaluation is often undertaken in chest pain clinics.
The full article is accessible to AMA members and paid subscribers. Login to read more or purchase a subscription now.
Please note: institutional and Research4Life access to the MJA is now provided through Wiley Online Library.
- 1. Neumann JT, Twerenbold R, Ojeda F, et al. Application of high‐sensitivity troponin in suspected myocardial infarction. N Engl J Med 2019; 380: 2529–2540.
- 2. Chew DP, Scott IA, Cullen L, et al; NHFA/CSANZ ACS Guideline 2016 Executive Working Group. National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: Australian clinical guidelines for the management of acute coronary syndromes 2016. Heart Lung Circ 2016; 25: 895–951.
- 3. Collet JP, Thiele H, Barbato E, et al; ESC Scientific Document Group. 2020 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST‐segment elevation. Eur Heart J 2020; https://doi.org/10.1093/eurheartj/ehaa575 [online ahead of print].
- 4. Black JA, Campbell JA, Parker S, et al. Absolute risk assessment for guiding cardiovascular risk management in a chest pain clinic. Med J Aust 2021; 214: 266–271.
- 5. Klimis H, Chow CK. Are we behind the times on cardiovascular risk assessment in Australia? Med J Aust 2020; 213: 168–169. https://www.mja.com.au/journal/2020/213/4/are-we-behind-times-cardiovascular-risk-assessment-australia
- 6. National Vascular Disease Prevention Alliance. Guidelines for the management of absolute cardiovascular disease risk. 2012. http://cvdcheck.org.au/pdf/Absolute_CVD_Risk_Full_Guidelines.pdf (viewed Feb 2021).
- 7. Chiuve S, McCullough ML, Sacks FM, Rimm EB. Healthy lifestyle factors in the primary prevention of coronary heart disease among men. Circulation 2006; 114: 160–167.
- 8. Jackevicius CA, Mamdani M, Tu JV. Adherence with statin therapy in elderly patients with and without acute coronary syndromes. JAMA 2002; 288: 462–467.
- 9. Jelinek MV, Santamaria JD, Thompson DR, Vale MJ. “FIT FOR PURPOSE”. The COACH program improves lifestyle and biomedical cardiac risk factors. Heart 2012; 98: 1608.
- 10. The SCOT‐HEART Investigators; Newby DE, Adamson PD, Berry C, et al. Coronary CT angiography and 5‐year risk of myocardial infarction. N Engl J Med 2018; 379: 924–933.
- 11. Mortensen MB, Dzaye O, Steffensen FH, et al. Impact of plaque burden versus stenosis on ischemic events in patients with coronary atherosclerosis. J Am Coll Cardiol 2020; 76: 2803–2813.
- 12. Venkataraman P, Stanton T, Liew D, et al. Coronary artery calcium scoring in cardiovascular risk assessment of people with family histories of early onset coronary artery disease. Med J Aust 2020; 213: 170–177. https://www.mja.com.au/journal/2020/213/4/coronary-artery-calcium-scoring-cardiovascular-risk-assessment-people-family
- 13. Kalia NK, Miller NG, Nasir K, et al. Visualising coronary calcium is associated with improvements in adherence with statin therapy. Atherosclerosis 2006; 185: 394–399.
Johannes Neumann is supported by a fellowship from the Deutsche Forschungsgemeinschaft (NE 2165/1‐1).
No relevant disclosures.