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New TGA warning label for use of NSAIDs in fluid-depleted children

Ronald P Batagol
Med J Aust 2014; 201 (7): . || doi: 10.5694/mja14.00959
Published online: 6 October 2014

To the Editor: Non-steroidal anti-inflammatory drugs (NSAIDs) have been very widely used for many years in Australia and elsewhere, in both prescription and non-prescription settings.


  • Melbourne, VIC.


Correspondence: healthy5555@hotmail.com

Competing interests:

No relevant disclosures.

  • 1. John CM, Saroha V, Jones C. Using nonsteroidal anti-inflammatory drugs in volume-depleted children can precipitate acute renal failure. Pediatrics 2008; 121 Suppl 2: S142.
  • 2. Moghal NE, Hegde S, Eastham KM. Ibuprofen and acute renal failure in a toddler. Arch Dis Child 2004; 89: 276-277.
  • 3. Deparment of Health Therapeutic Goods Administration. Medicines Advisory Statements Specification 2014. F2014L00693. http://www.comlaw.gov.au/Details/F2014L00693 (accessed Aug 2014).
  • 4. Adverse Drug Reactions Advisory Committee. ACE inhibitor, diuretic and NSAID: a dangerous combination. Aust Adv Drug React Bull 2003; 22: 14-15. http://www.tga.gov.au/hp/aadrb-0308.htm#.U_Q8SKMUwxg (accesssed Aug 2014).
  • 5. Kidney Health Australia. Kidney Health Australia urges caution on “triple whammy” risks [media release]. 10 Oct 2006.

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