A model of care is in place but the challenge of early detection remains
Familial hypercholesterolaemia (FH) is the most common and serious type of inherited hyperlipidaemia. It causes premature atherosclerotic cardiovascular disease (CVD), in particular coronary heart disease (CHD), bringing forward the onset of CVD by one to four decades.1
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- 5. Watts GF, Juniper A, van Bockxmeer F, et al. Familial hypercholesterolaemia: a review with emphasis on evidence for treatment, new models of care and health economic evaluations. Int J Evid Based Healthc 2012; 10: 211-221.
- 6. Williams RR, Hamilton-Craig I, Kostner GM, et al. MED-PED: An international project for the detection and improvement in management of familial hypercholesterolemia. In: Williams RR, editor. Preventive cardiovascular genetics. Geneva: World Health Organization, 1997.
- 7. Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents; National Heart, Lung, and Blood Institute. Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: summary report. Pediatrics 2011; 128 Suppl 5: S213-S256. Epub 2011 Nov 14.
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Ian Hamilton-Craig has received honoraria for consulting and lectures from the following pharmaceutical companies: Sanofi, Abbott, Merck Sharp & Dohme, Novartis, AstraZeneca, Pfizer, Amgen. Gerald Watts has received honoraria for consulting and lectures from the following pharmaceutical companies: Sanofi, Genzyme, Amgen, Abbott, Johnson & Johnson, Merck Sharp & Dohme, Novartis, AstraZeneca, GlaxoWelcome, Pfizer.