MJA
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Prevalence, pathogenesis and spectrum of neurological symptoms in COVID‐19 and post‐COVID‐19 syndrome

Josef Finsterer and Fulvio A Scorza
Med J Aust 2024; 220 (6): . || doi: 10.5694/mja2.52235
Published online: 1 April 2024

To the Editor: Wesselingh's narrative review is excellent but, in our view, omitted some potentially important points. The spectrum of central and peripheral nervous system complications of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infections is probably broader than stated in the review. In addition to the complications listed in the article (eg, headache, peripheral neuropathy, seizures, encephalitis, Guillain–Barré syndrome, movement disorders and cerebrovascular disease), the neurological symptoms of coronavirus disease 2019 (COVID‐19) may also include complications such as acute disseminated encephalomyelitis, acute haemorrhagic necrotising encephalitis, acute haemorrhagic leucoencephalitis, acute necrotising encephalopathy, multiple sclerosis, myelin oligodendrocyte glycoprotein‐associated disease, pituitary apoplexy, opsoclonus–myoclonus syndrome, cerebellitis, myelitis, myasthenia, myasthenic syndrome, myositis, myopathy and rhabdomyolysis. However, it is important to note that all of these potential complications are derived from observational studies that lacked a control group for comparison.

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