Lessons from practice Low attenuation lymphadenopathy on computed tomography leading to diagnosis of Whipple disease

A 48‐year‐old man of Eastern European origin presented to our hospital in Adelaide, Australia with a 3‐month history of increasing diarrhoea 8–10 times per day, cramping abdominal discomfort and weight loss of 8 kg. The patient had returned 3 months previously from his annual 6‐week holiday in Croatia. He had also been recently admitted to hospital with acute pulmonary oedema of uncertain aetiology, and had a 5‐year history of seronegative polyarthralgia and lethargy. He had been noted to have abdominal lymphadenopathy with splenomegaly on a computed tomography (CT) scan of the abdomen 3 years earlier, for which investigations with BCR‐ABL genetic analysis and serum protein electrophoresis showed no evidence of a lymphoproliferative disorder.