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Targeted physical activity for older adults with mild cognitive impairment and subjective cognitive decline

Emily You, Kathryn A Ellis, Kay Cox and Nicola T Lautenschlager
Med J Aust 2019; 210 (9): . || doi: 10.5694/mja2.50153
Published online: 20 May 2019

Tailored guidelines are needed to support strategies for dementia risk reduction

There is now international consensus that physical inactivity can be considered a modifiable risk factor for dementia.1 Research indicates that 6.5% of the attributable risk of dementia in the global population can be ascribed to low levels of physical activity alone,2 and engaging in physical activity is regarded as one of the strongest protective factors to reduce dementia risk.2 Extensive reviews of the evidence have led international health organisations, including the World Health Organization, the British National Institute of Health and Care Excellence and the American National Institutes of Health, to advocate for physical activity as both a primary prevention (in cognitively healthy individuals) and secondary prevention (in individuals who do not have dementia but already experience cognitive decline) strategy for reducing dementia risk.2,3,4 A recent American report further supports that physical activity has many benefits, with some (eg, stroke prevention) causally linked to brain health.3 While the evidence is still inconclusive, physical activity may delay or slow age‐related cognitive decline, and people are recommended to increase physical activity to gain this brain health benefit.3


  • 1 University of Melbourne, Melbourne, VIC
  • 2 Florey Institute of Neuroscience and Mental Health, Melbourne, VIC
  • 3 University of Western Australia, Perth, WA
  • 4 Aged Persons Mental Health Program, North Western Mental Health, Melbourne Health, Melbourne, VIC


Correspondence: Chuanmei.You@unimelb.edu.au

Acknowledgements: 

This project has been funded by the Dementia Centre for Research Collaboration as part of an initiative of the Commonwealth Government of Australia. We acknowledge financial support from the National Health and Medical Research Council Centre of Research Excellence in Cognitive Health (no. 1100579). We thank the project team members for their commitment to this project, and the advisory panel members for their invaluable support and advice.

Competing interests:

No relevant disclosures.

  • 1. World Health Organization. Global action plan on physical activity 2018–2030. WHO, 2018. https://www.who.int/ncds/prevention/physical-activity/global-action-plan-2018-2030/en (viewed Dec 2018).
  • 2. Livingston G, Sommerlad A, Orgeta V, et al. Dementia prevention, intervention, and care. Lancet 2017; 390: 2673–2734.
  • 3. National Academies of Sciences, Engineering, and Medicine; ealth and Medicine Division; Board on Health Sciences Policy; Committee on Preventing Dementia and Cognitive Impairment; Downey A, Stroud C, Landis S, Leshner AI, editors. Preventing cognitive decline and dementia: a way forward. Washington DC: National Academies Press, 2017: 4, 10, 12, 80.
  • 4. Neurology. Pointing the way to primary prevention of dementia. Lancet Neurol 2017; 16: 677.
  • 5. Brown WJ, Moorhead G, Marshall A. Choose health: be active — a physical activity guide for older Australians. Canberra: Commonwealth of Australia, 2008. http://www.health.gov.au/internet/main/publishing.nsf/content/phd-physical-choose-health (viewed Dec 2018).
  • 6. Piercy KL, Troiano RP, Ballard RM, et al. The physical activity guidelines for Americans. JAMA 2018; 320: 2020–2028.
  • 7. Tremblay MS, Kho ME, Tricco AC, Duggan M. Process description and evaluation of Canadian physical activity guidelines development. Int J Behav Nutr Phys Act 2010; 7: 42.
  • 8. Vancampfort D, Stubbs B, Lara E, et al. Mild cognitive impairment and physical activity in the general population: findings from six low‐ and middle‐income countries. Expe Gerontol 2017; 100: 100–105.
  • 9. Jessen F, Amariglio RE, van Boxtel M, et al. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease. Alzheimers Dement 2014; 10: 844–852.
  • 10. Winblad B, Palmer K, Kivipelto M, et al. Mild cognitive impairment‐beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment. J Intern Med 2004; 256: 240–246.
  • 11. Schepker CA, Leveille SG, Pedersen MM, et al. Effect of pain and mild cognitive impairment on mobility. J Am Geriatr Soc 2016; 64: 138–143.
  • 12. Jeon SY, Han SJ, Jeong JH, Fregni F. Effect of exercise on balance in persons with mild cognitive impairment. Neurorehabilitation 2014; 35: 271–278.
  • 13. Lautenschlager NL, Cox K, Hill KD, et al. Physical activity guidelines for older Australians with mild cognitive impairment or subjective cognitive decline. Melbourne: Dementia Collaborative Research Centres, 2018. https://medicine.unimelb.edu.au/__data/assets/pdf_file/0008/2672846/PAG.pdf (viewed Dec 2018).
  • 14. Winblad B, Amouyel P, Andrieu S, et al. Defeating Alzheimer's disease and other dementias: a priority for European science and society. Lancet Neurol 2016; 15: 455–532.
  • 15. Brodaty H, Sachdev F, Singh MAF, et al. Maintain your brain [website]. Sydney: Centre for Healthy Brain Ageing, UNSW Sydney, 2018. http://www.maintainyourbrain.org/meet-our-investigators.html (viewed Dec 2018).

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