A review of maturity onset diabetes of the young (MODY) and challenges in the management of glucokinase-MODY

We thank Flack and colleagues for their detailed comments on our review.1 The prevalence of gestational diabetes mellitus (GDM) of 5–10% was based on a prospective study by Moses and colleagues using the Australasian Diabetes in Pregnancy Society criteria, which found a prevalence in Wollongong, New South Wales, of 8.6–10.5% (9.6% overall).2 Using the more recently adopted International Association of Diabetes and Pregnancy Study Groups diagnostic definition in the same study, the prevalence of GDM was 13.0%. However, the cohort primarily comprised Australian women of European descent and the data were likely influenced by the slightly older maternal age; therefore, it may not reflect the national prevalence of GDM. Although other studies have produced a similar figure (eg, 13.6%),3 data from the National Perinatal Data Collection provided by the Australian Institute of Health and Welfare indicated a prevalence of 4.8%.4 Therefore, a range of 5–10% was deemed an adequate approximation. We agree with Flack and colleagues that certain multi-ethnic populations (eg, Bankstown-Lidcombe) will have higher GDM prevalence rates.