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Australian transplant recipients are at risk of chronic hepatitis E

James P Newcombe, Stella McGinn, Bruce Wong, Archie Darbar and George Kotsiou
Med J Aust 2017; 206 (7): . || doi: 10.5694/mja16.01204
Published online: 17 April 2017

Hepatitis E virus (HEV) genotype 3, the most common genotype in high income countries, is transmitted by ingestion of high risk food — including pork, deer and shellfish — and by blood transfusion. Rural residence, travel to hyperendemic areas (eg, southern Europe) and animal exposure are other risk factors.1


  • Royal North Shore Hospital, Sydney, NSW



Acknowledgements: 

We thank Paul Collett and David Waugh, renal physicians from the Royal North Shore Hospital, for their assistance with patient recruitment.

Competing interests:

No relevant disclosures.

  • 1. Kamar N, Bendall R, Legrand-Abravanel F, et al. Hepatitis E. Lancet 2012; 379: 2477-2488.
  • 2. Pas SD, de Man RA, Mulders C, et al. Hepatitis E virus infection among solid organ transplant recipients, the Netherlands. Emerg Infect Dis 2012; 18: 869-872.
  • 3. Shrestha AC, Seed CR, Flower RL, et al. Hepatitis E virus and implications for blood supply safety, Australia. Emerg Infect Dis 2014; 20: 1940-1942.
  • 4. Yapa CM, Furlong C, Rosewell A, et al. First reported outbreak of locally acquired hepatitis E virus infection in Australia. Med J Aust 2016; 204: 274. <MJA full text>
  • 5. Speers DJ, Ma MX, Faddy HM, et al. Domestically acquired hepatitis E successfully treated with ribavirin in an Australian liver transplant recipient. Med J Aust 2015; 202: 209-211. <MJA full text>
  • 6. Moal V, Legris T, Motte A, et al. Systematic serological testing for hepatitis E virus in kidney transplant recipients. J Clin Microbiol 2015; 53: 1523-1530.
  • 7. Pawlotsky JM. Hepatitis E screening for blood donations: an urgent need? Lancet 2014; 384: 1729-1730.
  • 8. NHS Blood and Transplant. Change to NHSBT pricing of products in 2017/18 and introduction of universal screening for hepatitis E [website]. Watford: NHS; 2016. http://www.nhsbt.nhs.uk/news-and-media/news-articles/news_2016_12_21.asp (accessed Jan 2017).
  • 9. Australian Red Cross Blood Service. Hepatitis E study kicks off [website]. Alexandria: ARCBS; 2016. http://www.transfusion.com.au/BSIB_July2016_8 (accessed Jan 2017).

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