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Reversal of end-stage renal failure using direct-acting antiviral agents for chronic hepatitis C

Tim Mitchell, Aron Chakera, Gary P Jeffrey, Leon A Adams, George Garas, Tamara Jones and Gerry MacQuillan
Med J Aust 2016; 205 (5): . || doi: 10.5694/mja16.00207
Published online: 5 September 2016

Clinical record


  • 1 Sir Charles Gairdner Hospital, Perth, WA
  • 2 University of Western Australia, Perth, WA



Competing interests:

No relevant disclosures.

  • 1. Bunchorntavakul C, Maneerattanaporn M, Chavalitdhamrong D. Management of patients with hepatitis C infection and renal disease. World J Hepatol 2015; 7: 213-225.
  • 2. Dammacco F, Sansonno D. Therapy for hepatitis C virus-related cryoglobulinemic vasculitis. N Engl J Med 2013; 369: 1035-1045.
  • 3. Sise ME, Bloom AK, Wisocky J, et al. Treatment of hepatitis C virus-associated mixed cryoglobulinemia with direct-acting antiviral agents. Hepatology 2016; 63: 408-417.
  • 4. Hezode C, Asselah T, Reddy KR, et al. Ombitasvir plus paritaprevir plus ritonavir with or without ribavirin in treatment-naive and treatment-experienced patients with genotype 4 chronic hepatitis C virus infection (PEARL-I): a randomised, open-label trial. Lancet 2015; 385: 2502-2509.
  • 5. Pockros PJ, Reddy KR, Mantry PS, et al. Safety of ombitasvir/paritaprevir/ritonavir plus dasabuvir for treating HCV Gt1 infection in patients with severe renal impairment or end-stage renal disease: the RUBY-1 study [abstract LO1]. J Hepatol 2015; 62 Suppl 2: S257.

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