MJA
MJA

Shigellosis: high rates of antibiotic resistance necessitate new treatment recommendations

Jeremy Brown, Simon J Willcox, Neil Franklin, Briony Hazelton and Matthew VN O'Sullivan
Med J Aust 2016; 204 (7): . || doi: 10.5694/mja15.01176
Published online: 18 April 2016

Shigella species cause a potentially severe diarrhoeal illness that is frequently travel-associated and is both foodborne and sexually acquired. There is evidence of increasing antibiotic resistance in Shigella isolates from international studies.1,2 However, there is limited published research on this issue in an Australian context. The current Australian Therapeutic Guidelines recommend either co-trimoxazole or quinolone therapy for suspected or proven shigellosis, but do comment that quinolone resistance is increasing in developing countries and recommend azithromycin as an alternative option, if required.3 Successful treatment of shigellosis reduces the duration of illness and infectivity.

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