Acute HIV infection presenting as erythema multiforme in a 45-year-old heterosexual man

Ma and colleagues have provided an excellent description of an unusual presentation of HIV infection, erythema multiforme, in a heterosexual man.1 This “lesson from practice” comes in a long line of similar salutary cases published in the Journal, where we are reminded that HIV infection is not only seen in key populations — predominantly men who have sex with men (MSM) — in Australia. These have included the elderly,2 female returned travellers3 and heterosexual middle-aged men.1 In 2014, about 30% of new HIV infection diagnoses in Australia were not in individuals identified as MSM.4 In our cohort those who present late (with a low CD4 lymphocyte count) are less likely to self-identify as MSM.