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Renal replacement therapy associated with lithium nephrotoxicity in Australia

J Elisabeth Wells
Med J Aust 2015; 202 (1): . || doi: 10.5694/mja14.01216
Published online: 19 January 2015

To the Editor: Adam1 contends that Roxanas and colleagues2 have overemphasised the risk of renal replacement therapy (RRT) associated with lithium treatment. I disagree.


  • University of Otago, Christchurch, New Zealand.


Correspondence: elisabeth.wells@otago.ac.nz

Competing interests:

No relevant disclosures.

  • 1. Adam WR. Renal replacement therapy associated with lithium nephrotoxicity in Australia [letter]. Med J Aust 2014; 201: 30. <MJA full text>
  • 2. Roxanas M, Grace BS, George CRP. Renal replacement therapy associated with lithium nephrotoxicity in Australia. Med J Aust 2014; 200: 226-228. <MJA full text>
  • 3. Bendz H, Schon S, Attman P, Aurell M. Renal failure occurs in chronic lithium treatment but is uncommon. Kidney Int 2010; 77: 219-224.
  • 4. Aiff H, Attman P-O, Aurell M, et al. End-stage renal disease associated with prophylactic lithium treatment. Eur Neuropsychopharmacol 2014; 24: 540-544.
  • 5. Close H, Reilly J, Mason JM, et al. Renal failure in lithium-treated bipolar disorder: a retrospective cohort study. PLOS One 2014; 9: e90169. doi: 10.1371/journal.pone.0090169.

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