To the Editor: Clarke and Avery make an important point highlighting the substantial costs arising from a loophole allowing multibrand fixed-dose combinations (FDCs) listed on the Pharmaceutical Benefits Scheme (PBS) to retain price premiums long after premiums on their individual components have eroded.1
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The George Institute for Global Health secured an exclusive global licence in December 2012 for the polypills used in recent trials, following a decision by Dr Reddy's Laboratories Ltd not to proceed with taking the products to market because of existing regulatory requirements.