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Renal sympathetic denervation for resistant hypertension in a patient with a single kidney

Bo Xu and Robert J Whitbourn
Med J Aust 2014; 200 (4): . || doi: 10.5694/mja13.00003
Published online: 3 March 2014

To the Editor: We report a case of successful renal sympathetic denervation (RSD) treatment for resistant hypertension in a patient with a single kidney.1-3 RSD is performed via femoral arterial access, using a radiofrequency ablation catheter to deliver energy to the renal artery wall. When delivering RSD to a single kidney, potential renal artery vascular complications can have a significant negative impact on a patient’s renal function, compared with patients with two functioning kidneys.


  • St Vincent’s Hospital, Melbourne, VIC.


Correspondence: bo.xu@svhm.org.au

Competing interests:

Robert Whitbourn has received institutional grants and honoraria from Medtronic.

  • 1. Krum H, Schlaich M, Whitbourn R, et al. Catheter-based renal sympathetic denervation for resistant hypertension: a multi-centre safety and proof-of-principle cohort study. Lancet 2009; 373: 1275-1281.
  • 2. Symplicity HTN-2 Investigators. Renal sympathetic denervation in patients with treatment-resistant hypertension (the Symplicity HTN-2 Trial): a randomised controlled trial. Lancet 2010; 376: 1903-1909.
  • 3. Palmer SC, Judkins C, Williams PD, Whitbourn RJ. Renal sympathetic nerve denervation for the treatment of resistant hypertension. Med J Aust 2013; 199: 160-162. <MJA full text>
  • 4. Dorr O, Hamm C, Nef HM. Single-side renal sympathetic denervation in a hypertensive patient with a single kidney. Am J Kidney Dis 2013; 61: 1042-1043.

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