Evidence of improved detection using integrated 2D and 3D mammography provides opportunity for Australia to lead screening trials
The STORM (Screening with Tomosynthesis or Standard Mammography) trial, from a team of Italian and Australian researchers, reports the world’s first completed population breast screening trial of integrated 2-dimensional (2D) and 3-dimensional (3D) mammography.1 Using breast tomosynthesis, a pseudo-3D derivative of digital mammography, in combination with 2D mammography, STORM researchers found that breast cancer detection was significantly increased when screen-reading was performed using integrated 2D and 3D mammography compared with 2D mammography alone (Box).1 The trial also showed that this screening method could significantly reduce false-positive results (Box). These data provide evidence that integrated 2D and 3D mammography would enhance breast screening performance measures, and are consistent with the interim findings of another population screening study conducted in Oslo, Norway, using the same mammographic technology.2
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I receive research support through a National Breast Cancer Foundation Practitioner Fellowship.
The STORM trial was conducted in Italy with support from Hologic (Hologic, United States, and Technologic, Italy) through provision of tomosynthesis technology. I was the scientific director of the trial.