To the Editor: In 2009, we reported on increases in the level of cardiac troponin (using the TnI-Ultra troponin I assay [Siemens Healthcare Diagnostics]) among runners in the Perth marathon.1 Of the 88 runners enrolled, raised troponin levels were seen in 28 participants (32%). The independent predictors were weight loss and an increase in creatinine levels.
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- 1 Emergency Medicine, Royal Perth Hospital, University of Western Australia, Perth, WA.
- 2 Western Australian Institute for Medical Research, University of Western Australia, Perth, WA.
- 3 Royal Perth Hospital, Perth, WA.
Correspondence: daniel.fatovich@health.wa.gov.au
- 1. Hubble KM, Fatovich DM, Grasko JM, Vasikaran SD. Cardiac troponin increases among marathon runners in the Perth Marathon: the Troponin in Marathons (TRIM) study. Med J Aust 2009; 190: 91-93. <MJA full text>
- 2. Mingels A, Jacobs L, Michielsen E, et al. Reference population and marathon runner sera assessed by highly sensitive cardiac troponin T and commercial cardiac troponin T and I assays. Clin Chem 2009; 55: 101-108.
- 3. Scott IA, Cullen L, Tate JR, Parsonage W. Highly sensitive troponin assays — a two-edged sword? Med J Aust 2012; 197: 320-323. <MJA full text>
- 4. Thygesen K, Alpert JS, Jaffe AS, et al. Third universal definition of myocardial infarction. Eur Heart J 2012; 33: 2551-2567.
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