MJA
MJA

Echocardiographic monitoring for clozapine-associated cardiac toxicity — time for review?

Stuart D Murch, David L Prior and David J Castle
Med J Aust 2013; 198 (2): . || doi: 10.5694/mja11.11394
Published online: 4 February 2013

To the Editor: Clozapine therapy is a recognised risk factor for myocarditis and cardiomyopathy; however, there are no national guidelines for cardiac monitoring. Similar to many centres in Australia, and consistent with the consensus view from major psychiatric facilities in Victoria,1 our institution’s policy is to monitor patients with a baseline echocardiogram before starting treatment with clozapine, at 6 months and 12 months after starting treatment, and once per year thereafter.

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