To the Editor: The recent editorial by Kefford1 fails to mention that (i) the 5-year survival for malignant melanoma is excellent at 89% for males and 91% for females; (ii) treatment with the new melanoma drug ipilimumab for the 1279 people who died from melanoma in 2007 would cost the Australian Government $156 million based on the quoted drug cost of $120 000 for a course of four injections; and (iii) the increase in survival is only minimal with ipilimumab (median survival, 10.1 months v 6.4 months for placebo).2
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- 1. Kefford RF. Drug treatment for melanoma: progress, but who pays? Med J Aust 2012; 197: 198-199. <MJA full text>
- 2. Hodi FS, O’Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010; 363: 711-723.
- 3. Fife KM, Colman MH, Stevens GN, et al. Determinants of outcome in melanoma patients with cerebral metastases. J Clin Oncol 2004; 22: 1293-1300.
- 4. Australian Government Department of Health and Ageing. Pharmaceutical Benefits Scheme. PBS expenditure and prescriptions. Table 5: ATC main group comparison (incl drs bag), years ending Jun 2003 to Jun 2011. http://www. health.gov.au/internet/main/publishing.nsf/Content/pbs_expenditure_prescriptions-copy1 (accessed Aug 2012).
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