With the completion of the first liver–intestinal transplant in Australia in July 2010, the Austin Hospital in Victoria became one of only 35 active centres worldwide to offer this life-saving procedure to patients with irreversible intestinal failure and associated life-threatening complications of parenteral nutrition.
A 32-year-old man was initially referred to our centre in 2005 after the progression of multiple complications of long-term parenteral nutrition (PN) for short gut syndrome. He had concomitant bilateral hydronephrosis and dilated renal pelvises, suggesting a visceral myopathy. A long-strip rectal biopsy confirmed hypoganglionosis.
The full article is accessible to AMA members and paid subscribers. Login to read more or purchase a subscription now.
Please note: institutional and Research4Life access to the MJA is now provided through Wiley Online Library.
- 1. Kirkman RL. Small bowel transplantation. Transplantation 1984; 37: 429-433.
- 2. Abu-Elmagd K, Bond G, Reyes J, Fung J. Intestinal transplantation: a coming of age. Adv Surg 2002; 36: 65-101.
- 3. Intestinal Transplant Association. Intestinal transplant registry report. Proceedings of the XII International Small Bowel Transplant Symposium; 2011 Sep 15-18; Washington DC.
- 4. Abu-Elmagd KM, Costa G, Bond GJ, et al. Five hundred intestinal and multivisceral transplantations at a single center: major advances with new challenges. Ann Surg 2009; 250: 567-581.
- 5. Howard L, Heaphey L, Fleming CR, et al. Four years of North American registry home parenteral nutrition outcome data and their implications for patient management. J Parenter Enteral Nutr 1991; 15: 384-393.
- 6. Chan S, McCowen KC, Bistrian BR, et al. Incidence, prognosis, and etiology of end-stage liver disease in patients receiving home total parenteral nutrition. Surgery 1999; 126: 28-34.
- 7. Buchman AL, Iyer K, Fryer J. Parenteral nutrition-associated liver disease and the role for isolated intestine and intestine/liver transplantation. Hepatology 2006; 43: 9-19.
- 8. Fishbein TM, Matsumoto CS. Intestinal replacement therapy: timing and indications for referral of patients to an intestinal rehabilitation and transplant program. Gastroenterology 2006; 130 (2 Suppl 1): S147-S151.
- 9. Fishbein TM. Intestinal transplantation. N Engl J Med 2009; 361: 998-1008.
- 10. Garg M, Jones RM, Vaughan RB, Testro AG. Intestinal transplantation: current status and future directions. J Gastroenterol Hepatol 2011; 26: 1221-1228.
- 11. Horslen SP. Optimal management of the post-intestinal transplant patient. Gastroenterology 2006; 130 (2 Suppl 1): S163-S169.
- 12. Abu-Elmagd KM. Intestinal transplantation for short bowel syndrome and gastrointestinal failure: current consensus, rewarding outcomes, and practical guidelines. Gastroenterology 2006; 130 (2 Suppl 1): S132-S137.
- 13. Sudan D. Cost and quality of life after intestinal transplantation. Gastroenterology 2006; 130 (2 Suppl 1): S158-S162.
No relevant disclosures.