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Testing the golden rules of infectious diseases: staphylococcal bacteriuria is predictive of staphylococcal bacteraemia

Janine M Trevillyan and Denis Spelman
Med J Aust 2012; 197 (3): . || doi: 10.5694/mja12.10610
Published online: 6 August 2012

To the Editor: Medical students around the world are taught that staphylococcal bacteriuria may be indicative of concurrent bacteraemia.1 Yet there is little published evidence to support this “golden rule” of infectious diseases, and a retrospective review has suggested that no such relationship exists.2


  • Alfred Hospital, Melbourne, VIC.


Correspondence: j.trevillyan@alfred.org.au

Competing interests:

No relevant disclosures.

  • 1. Yung A, Spelman D, Street A, et al, editors. Infectious diseases: a clinical approach. 3rd ed. Melbourne: IP Communications, 2010.
  • 2. Ekkelenkamp MB, Verhoef J, Bonten MJ. Quantifying the relationship between Staphylococcus aureus bacteremia and S. aureus bacteriuria: a retrospective analysis in a tertiary care hospital. Clin Infect Dis 2007; 44: 1457-1459.
  • 3. Lee BK, Crossley K, Gerding DN. The association between Staphylococcus aureus bacteremia and bacteriuria. Am J Med 1978; 65: 303-306.
  • 4. Pulcini C, Matta M, Mondain V, et al. Concomitant Staphylococcus aureus bacteriuria is associated with complicated S. aureus bacteremia. J Infect 2009; 59: 240-246.
  • 5. Gorrill RH. The establishment of staphylococcal abscesses in the mouse kidney. Br J Exp Pathol 1958; 39: 203-212.

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