MJA
MJA

In Other Journals

Alison Williams
Med J Aust 2010; 193 (7): . || doi: 10.5694/j.1326-5377.2010.tb03977.x
Published online: 4 October 2010

Hair samples may provide insight into stress levels preceding myocardial infarction (MI), according to a Canadian study. Although the association between acute stress and MI is well recognised, research into the role of chronic stress has been limited by recall bias and lack of a reliable biological marker. The stress hormone cortisol, which accumulates in hair, may be just such a marker. As hair grows at a rate of about 1 cm per month, the researchers measured cortisol levels in the proximal 3 cm of scalp hair to reflect stress levels in the previous 3 months. The study, claimed to be the first to use hair samples for this purpose, found that median cortisol levels were significantly higher in the 56 MI patients (P = 0.006) compared with controls. On multivariate analysis, hair cortisol levels had a stronger correlation with MI than other risk factors such as body mass index and cholesterol levels (OR, 17.4; 95% CI, 2.15-140.5). Patients with raised hair cortisol levels may therefore benefit from more aggressive management of cardiovascular risk factors.

Online responses are no longer available. Please refer to our instructions for authors page for more information.