Isoniazid hypersensitivity  in a child

Merritt, Tony D; Massey, Peter D

doi:10.5694/j.1326-5377.2009.tb02464.x

Topics

To the Editor: Isoniazid is used extensively for the treatment of active and latent tuberculosis (TB). It is generally well tolerated by children, and hypersensitivity reactions resulting in skin rash and requiring cessation of treatment are rarely reported in this age group.1,2

1 Hunter New England Population Health, Newcastle, NSW.
2 Hunter New England Population Health, Tamworth, NSW.

Correspondence: tony.merritt@hnehealth.nsw.gov.au

1. Altet Gómez MN, Alcáide Megías J, Boque Genovard MA. [Toxicity in the current treatment of tuberculosis in children] [Spanish]. An Esp Pediatr 1984; 20: 18-27.
2. Padmini R, Srinivasin S, Nalini P, Mahadevan S. Short course chemotherapy for pulmonary tuberculosis in children. J Trop Pediatr 1993; 39: 361-364.
3. NSW Health. Tuberculosis contact tracing. Policy directive PD2008_017. 7 Apr 2008. http://www.health.nsw.gov.au/policies/pd/2008/pdf/PD2008_017.pdf (accessed Mar 2009).

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