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Relapsing polychondritis or ANCA-negative Wegener’s granulomatosis?

Weekitt Kittisupamongkol and Wanla Kulwichit
Med J Aust 2007; 187 (8): . || doi: 10.5694/j.1326-5377.2007.tb01376.x
Published online: 15 October 2007

To the Editor: In their recent Snapshot, Sharma and colleagues reported an interesting case of a woman presenting with prolonged fever and inflammation of external ears, nose, and throat.1 On the basis of negative antineutrophil cytoplasmic antibodies (ANCAs), a diagnosis of relapsing polychondritis was made and the possibility of Wegener’s granulomatosis “ruled out”. Corticosteroid and azathioprine were given to the patient accordingly.


  • 1 Surin Hospital, Surin, Thailand.
  • 2 Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.


Correspondence: wkulwich@gmail.com

  • 1. Sharma A, Bambery P, Wanchu A, et al. A woman with abnormal ears and an unusual voice. Med J Aust 2007; 186: 424. <MJA full text>
  • 2. D’Cruz DP, Baguley E, Asherson RA, Hughes GR. Ear, nose, and throat symptoms in subacute Wegener’s granulomatosis. BMJ 1989; 299: 419-422.
  • 3. Small P, Black M, Davidman M, et al. Wegener’s granulomatosis and relapsing polychondritis: a case report. J Rheumatol 1980; 7: 915-918.
  • 4. Bosch X, Guilabert A, Font J. Antineutrophil cytoplasmic antibodies. Lancet 2006; 368: 404-418.

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