To the Editor: I read with interest the excellent review article on the metabolic syndrome by Chew et al in the 16 October 2006 issue of the Journal.1 In their article the authors claim there is a lack of data about the relationship between hyperinsulinaemia and changes in free testosterone levels.
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- School of Public Health and Clinical Nutrition, University of Kuopio, Kuopio, Finland.
Correspondence: tomipekka.tuomainen@uku.fi
- 1. Chew GT, Gan SK, Watts GF. Revisiting the metabolic syndrome. Med J Aust 2006; 185: 445-449. <MJA full text>
- 2. Laaksonen DE, Niskanen L, Punnonen K, et al. The metabolic syndrome and smoking in relation to hypogonadism in middle-aged men: a prospective cohort study. J Clin Endocrinol Metab 2005; 90: 712-719. http://jcem.endojournals.org/cgi/content/full/90/2/712 (accessed May 2007).
- 3. Laaksonen DE, Niskanen L, Punnonen K, et al. Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men. Diabetes Care 2004; 27: 1036-1041.
- 4. Laaksonen DE, Niskanen L, Punnonen K, et al. Sex hormones, inflammation and the metabolic syndrome: a population-based study. Eur J Endocrinol 2003; 149: 601-608.
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