A woman presenting with recurrent purpura fulminans was eventually found to have inflammatory bowel disease. We suggest the inflammatory state resulted in a deficiency of functional protein C.
A 28-year-old woman presented to hospital with a 1-week history of diarrhoea (three soft, non-bloody stools daily), 2 days of vomiting, and a 12-hour history of a purpuric truncal rash.
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- 1. Stein RH, Sapadin AN. Purpura fulminans. Int J Dermatol 2003; 42: 130-131.
- 2. Nolan J, Sinclair R. Review of management of purpura fulminans and two case reports. Br J Anaesth 2001; 86: 581-586.
- 3. Ward KM, Celebi JT, Gmyrek R, et al. Acute infectious purpura fulminans associated with asplenism or hyposplenism. J Am Acad Dermatol 2002; 47: 493-496.
- 4. Gurgey A, Aytac S, Kanra G, et al. Outcome in children with purpura fulminans: report on 16 patients. Am J Hematol 2005; 80: 20-25.
- 5. Warner PM, Kagan RJ, Yakuboff KP, et al. Current management of purpura fulminans: a multicenter study. J Burn Care Rehabil 2003; 24: 119-126.
- 6. Childers BJ, Cobanov B. Acute infectious purpura fulminans: a 15-year retrospective review of 28 consecutive cases. Am Surg 2003; 69: 86-90.
- 7. Smith OP, White B. Infectious purpura fulminans: diagnosis and treatment. Br J Haematol 1999; 104: 202-207.
- 8. Kravitz GR, Dries DJ, Peterson ML, et al. Purpura fulminans due to Staphylococcus aureus. Clin Infect Dis 2005; 40: 941-947.
- 9. Kempton CL, Bagby G, Collins JF. Ulcerative colitis presenting as purpura fulminans. Inflamm Bowel Dis 2001; 7: 319-322.
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We would like to thank Dr Chong Ong, who supplied one of the clinical pictures.
None identified.