Lung transplantation in Australia: barriers to translating new evidence into clinical practice | The Medical Journal of Australia
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Lung transplantation in Australia: barriers to translating new evidence into clinical practice

Greg Snell, Tom Kotsimbos and Trevor J Williams
Med J Aust 2006; 184 (9): . || doi: 10.5694/j.1326-5377.2006.tb00311.x
Published online: 1 May 2006

Evidence “beyond reasonable doubt” may never be achievable for low-volume drugs

The recent publication of a randomised controlled trial (RCT) of inhaled cyclosporin in the New England Journal of Medicine represents another milestone in the evolution of lung transplantation (LTx) as a standard therapy in the management of severe lung and pulmonary vascular diseases., RCTs have been few and far between in lung transplantation, and this is the first in such a high-profile general journal. However, the big question is: how will we integrate the study results into the clinical practice in Australia?

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