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Efficacy of an alcohol/chlorhexidine hand hygiene program in a hospital with high rates of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection

Keith V Woollard
Med J Aust 2006; 184 (5): . || doi: 10.5694/j.1326-5377.2006.tb00221.x
Published online: 6 March 2006

To the Editor: Johnson et al detailed an intensive hand hygiene program planned to reduce the burden of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infections.1 The results were based on observations before and after the program. Hand hygiene compliance rates reached only 42% despite the program, and there was no effect on patient MRSA colonisation or environmental colonisation or contamination. Outside the intensive care unit, there was no effect on health care worker colonisation. Despite this evidence of ineffectiveness, the program was held responsible for a reduction in hospital-wide rates of clinically important MRSA infections.


  • Murdoch Medical Centre, Suite 34, 100 Murdoch Drive, Murdoch, WA 6015.



  • 1. Johnson PDR, Martin R, Burrell LJ, et al. Efficacy of an alcohol/chlorhexidine hand hygiene program in a hospital with high rates of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection. Med J Aust 2005; 183: 509-519. <MJA full text>
  • 2. Clinical evidence. London: BMJ Publishing Group Ltd, 2005.
  • 3. Mortimer EA Jr, Lipsitz PJ, Wolinsky E, et al. Transmission of staphylococci between newborns. Importance of the hands to personnel. Am J Dis Child 1962; 104: 289-295.
  • 4. Huynh NT, Commens CA. Scrubbing for cutaneous procedures can be hazardous. Aust J Dermatol 2002; 43: 102-104.

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