In reply: Geneticists and counsellors must be able to calculate risks according to professional standards, regardless of whether modified risks lead to decision changes. Does training in genetic risk calculation help? Only 21% of our respondents who had had such training recently (< 3 years ago) estimated all target risks correctly. In response to Kirk et al, calculating conditional risks need not be time-consuming in scenarios similar to our target pedigrees,1 and is often helpful when at-risk (grand)parents do not wish to be tested but their offspring do.
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