Tramadol and new-onset seizures

Angelo Labate,* Mark R Newton,^† Graeme M Vernon,^‡ Samuel F Berkovic^§

Correspondence: s.berkovic@unimelb.edu.au

1. Kahn LH, Alderfer RJ, Graham DJ. Seizures reported with tramadol. JAMA 1997; 278: 1661.
2. Gasse C, Derby L, Vasilakis-Scaramozza C, Jick H. Incidence of first-time idiopathic seizures in users of tramadol. Pharmacotherapy 2000; 20: 629-634.
3. Gardner JS, Blough D, Drinkard CR, et al. Tramadol and seizures: a surveillance study in a managed care population. Pharmacotherapy 2000; 20: 1423-1431.
4. Jick H, Derby LE, Vasilakis C, Fife D. The risk of seizures associated with tramadol. Pharmacotherapy 1998; 18: 607-611.
5. King MA, Newton MR, Jackson GD, et al. Epileptology of the first-seizure presentation: a clinical, electroencephalographic, and magnetic resonance imaging study of 300 consecutive patients. Lancet 1998; 352: 1007-1011.
6. Australian Government. Health Insurance Commission. Available at: www.hic.gov.au/statistics/dyn_pbs/forms/pbs_tab1.shtml (accessed Nov 2004).

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