Age-related macular degeneration and its possible prevention

Constable, Ian J

doi:10.5694/j.1326-5377.2004.tb06401.x

Topics

Despite well publicised claims of the therapeutic value of dietary supplements and other new treatments, the evidence for their effectiveness is modest

Lions Eye Institute, Centre for Ophthalmology and Visual Science, University of Western Australia, Nedlands, WA.

Correspondence:

1. Mitchell P, Smith W, Attebo K, et al. Prevalence of age-related maculopathy in Australia. The Blue Mountains Eye Study. Ophthalmology 1995; 102: 1450-1460.
2. Klein R, Davis MD, Mogli YL, et al. The Wisconsin age-related maculopathy grading system. Ophthalmology 1991; 98: 1128-1134.
3. Macular Photocoagulation Study Group. Laser photocoagulation for juxtafoveal choroidal neovascularization. Five-year results from randomized clinical trials. Arch Ophthalmol 1994; 112: 500-509.
4. TAP Study Group. Verteporfin therapy for subfoveal choroidal neovascularization in age-related macular degeneration: three-year results of an open-label extension of two randomized clinical trials. TAP Report No. 5. Arch Ophthalmol 2002; 120: 1307-1314.
5. Klaver CC, Wolfs RC, Assink JJ, et al. Genetic risk of age-related maculopathy. Arch Ophthalmol 1998; 116: 1646-1651.
6. Klein R, Klein BE, Linton KL, et al. The Beaver Dam Eye Study: the relationship of age-related maculopathy to smoking. Am J Epidemiol 1993; 137: 190-200.
7. Seddon JM, Rosner B, Sperduto RD, et al. Dietary fat and risk for advanced age-related macular degeneration. Arch Ophthalmol 2001; 119: 1191-1199.
8. Cho E, Hung S, Willeton W, et al. Prospective study of dietary fat and risk of age-related macular degeneration. Am J Clin Nutr 2001; 73: 209-218.
9. Seddon JM, Cote J, Rosner B. Progression of age-related macular degeneration: association with dietary fat, transunsaturated fat, nuts, and fish intake. Arch Ophthalmol 2003; 121: 1728-1737.
10. Snow K, Seddon J. Do age-related macular degeneration and cardiovascular disease share common antecedents? Ophthalmic Epidemiol 1999; 6: 125-143.
11. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss. AREDS Report No. 8. Arch Ophthalmol 2001; 119: 1417-1436.

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