Connect
MJA
MJA

Megadose vitamin C in treatment of the common cold: a randomised controlled trial

Luis Vitetta, Avni Sali, Bill Paspaliaris and Nicola J Reavley
Med J Aust 2002; 176 (5): . || doi: 10.5694/j.1326-5377.2002.tb04393.x
Published online: 4 March 2002

To the Editor: There is much conflicting evidence that increased intake of vitamin C enhances the natural protective mechanisms of the body and decreases both the incidence and severity of the common cold.1


  • Graduate School of Integrative Medicine, Swinburne University Of Technology, Melbourne, VIC.



  • 1. Douglas RM, Chalker EB, Treacy B. Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev 2000; 2: CD000980.
  • 2. Audera C, Patulny RV, Sander BH, Douglas RM. Mega-dose vitamin C in treatment of the common cold: a randomised controlled trial. Med J Aust 2001; 175: 359-362. <eMJA full text>
  • 3. Smith A, Tyrrell D, Coyle K, et al. Diurnal variation in the symptoms of colds and influenza. Chronobiol Int 1988; 5: 411-416.
  • 4. Cohen S, Tyrrell DA, Russell MA, et al. Smoking, alcohol consumption, and susceptibility to the common cold. Am J Public Health 1993; 83: 1277-1283.
  • 5. Pamuk E, Byers T, Coates R, et al. Effect of smoking on serum nutrient concentrations in African–American women. Am J Clin Nutr 1994; 59: 891-895.
  • 6. Kleszczewski T, Kleszczewska E. FIA of vitamin C in blood serum in humans at increasing ethanol concentration. J Pharm Biomed Anal 2001; 25: 477-481.
  • 7. Takkouche B, Regueira C, Gestal-Otero JJ. A cohort study of stress and the common cold. Epidemiology 2001; 12: 345-349.
  • 8. Audera C, Patulny RV, Sander BH, Douglas RM. Mega-dose vitamin C in treatment of the common cold: a randomised controlled trial. Med J Aust 2001; 175: 359-362. <eMJA full text>
  • 9. Tyrrell DJ, Craig JW, Meade TW, White TA. A trial of ascorbic acid in the treatment of the common cold. Br J Prev Soc Med 1977; 31: 189-191.
  • 10. Douglas RM, Chalker EB, Treacy B. Vitamin C for preventing and treating the common cold (Cochrane Review). In: The Cochrane Library 3, 2001. Oxford: Update Software.

Author

remove_circle_outline Delete Author
add_circle_outline Add Author

Comment
Do you have any competing interests to declare? *

I/we agree to assign copyright to the Medical Journal of Australia and agree to the Conditions of publication *
I/we agree to the Terms of use of the Medical Journal of Australia *
Email me when people comment on this article

Online responses are no longer available. Please refer to our instructions for authors page for more information.