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Bisphosphonates and osteonecrosis of the jaw

Patrick M Purcell and Ian W Boyd
Med J Aust 2005; 182 (8): . || doi: 10.5694/j.1326-5377.2005.tb06762.x
Published online: 18 April 2005

Clinical records


  • Adverse Drug Reactions Unit, Therapeutic Goods Administration, Department of Health and Ageing, Canberra, ACT.


Correspondence: 

Acknowledgements: 

We acknowledge the contributions of Dr John McEwen, (Principal Medical Adviser, Therapeutic Goods Administration) and Associate Professor Duncan Topliss (Chairperson, ADRAC) to the preparation of this report.

Competing interests:

None identified.

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  • 8. Lugassy G, Shaham R, Nemets A, et al. Severe osteomyelitis of the jaw in long-term survivors of multiple myeloma: a new clinical entity. Am J Med 2004; 117: 440-441.
  • 9. The Maxillofacial Center for Diagnostics and Research. The history of maxillofacial osteonecrosis. Available at: http://maxillofacialcenter.com/NICOhistory.html (accessed Feb 2005).
  • 10. Novartis Pharmaceuticals Australia. Aredia product information. Sydney: Novartis, May 2004.
  • 11. Greenberg MS. Intravenous bisphosphonates and osteonecrosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 98: 259-260.

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