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Control of genital chlamydial infection in the Kimberley region of Western Australia

MJA 2004; 180 (1): 45

Donna B Mak,* Graeme H Johnson, Lewis J Marshall, Jacqueline K Mein§

* Public Health Physician, Department of Health Western Australia, 189 Royal Street, East Perth, WA 6000; † Medical Officer, Derby Aboriginal Health Service, Derby, WA; ‡ Head, Sexual Health Service, Fremantle Hospital, Fremantle, WA; § Public Health Medical Officer, Kimberley Population Health Unit, Broome, WA. makhoATbigpond.com

To the Editor: We were pleased to read Chen and Donovan’s editorial which highlighted sex-based inequalities in control of genital chlamydial infection and argued for more screening of men for this infection.1 In the Kimberley region of Western Australia, where rates of genital chlamydial infection are among the highest in Australia, control strategies encompass both sexes.2

Although chlamydial infection was not notifiable in WA until 1993, it has been part of the sexually transmitted infections (STI) control program of the Kimberley Public Health Unit (now the Kimberley Population Health Unit) since the 1980s. Since 1989, regional STI management guidelines have recommended that testing for chlamydial infection (and gonorrhoea, syphilis, hepatitis B and HIV infection) be offered to all patients presenting with STI symptoms or as a sexual contact of an STI patient, and as part of antenatal, prison and well-person’s screenings.3,4

In 1996, empirical treatment for chlamydial infection with single-dose azithromycin (funded by the Kimberley Public Health Unit) was added to the standard treatment regimen, and antibody testing and culture were replaced by nucleic acid testing, which is more transport-robust and sensitive. This led to the introduction in 1997 of active health-service-initiated contact tracing for chlamydial infection (ie, sexual contacts reported by patients with chlamydial infection are actively sought by health staff and offered an STI consultation and empirical treatment).

Between 11 June 2001 and 29 June 2002, WA Health Department staff (who contribute over 70% of the region’s STI notifications) notified 94 cases of chlamydial infection in female patients and 56 in male patients.5 Coinfection was common, with 61 patients (41%) also having gonorrhoea and four (3%) also having syphilis. Of the female patients, 30% were tested for chlamydia because they had self-presented with STI symptoms, 32% as part of antenatal or well-person’s screening, 36% because they had been reported as a sexual contact of a patient with STI, and 2% for unknown reasons. The corresponding proportions in male patients were 45%, 7%, 45% and 4%, respectively (Pearson χ2 = 12.6, df = 3; P = 0.006).

Prevalence of chlamydial infection in the Kimberley antenatal population (69% of whom are screened for chlamydia) is 3% (95% CI, 2%–6%).6 Prevalence in 93 Kimberley men screened consecutively on admission to prison during 18 weeks in 1998–1999 was also 3% (95% CI, 1%–9%). During this same period, prevalence among 59 Kimberley men and 68 women presenting consecutively as STI contacts was 19% (95% CI, 11%–31%) and 22% (95% CI, 14%–33%), respectively (Mak DB, unpublished data).

These data demonstrate that contact tracing contributes significantly to chlamydial case-finding, and support the addition of azithromycin to the Kimberley’s empirical STI treatment regimen.

Empirical treatment and contact tracing for gonorrhoea over more than 15 years have been associated with decreases in the rate of gonorrhoea and the male : female ratio of cases in the Kimberley (Box). Seven to 8 years after introducing empirical treatment and contact tracing for chlamydial infection, rates have increased in both sexes, as has the proportion of male notifications (Box). Further progress in control of chlamydial infection requires continued provision of STI screening, treatment and contact-tracing services that are acceptable and accessible to both men and women.

Notifications of chlamydial infection and gonorrhoea in the Kimberley region, 1993–2002 

  1. Chen MY, Donovan B. Screening for genital Chlamydia trachomatis infection: are men the forgotten reservoir [editorial]? Med J Aust 2003; 179: 124-125. <eMJA full text> <PubMed>
  2. Lin M, Roche P, Spencer J, et al. Australia’s notifiable diseases status, 2000. Annual report of the National Notifiable Diseases Surveillance System. Commun Dis Intell 2002; 26: 118-203. <PubMed>
  3. Carey M. Handbook on sexually transmissible diseases for community health staff Kimberley region. Derby: Disease Control Unit, 1989.
  4. Health Department of Western Australia. Guidelines for managing sexually transmitted infections: a guide for primary health care providers. Perth: Public Health Division of the Health Department of Western Australia, 2001.
  5. Mak D. Chlamydia and gonorrhoea notifications by practitioner type. Kimberley Public Health Unit Bull 2002; (Aug): 14. <PubMed>
  6. Mak DB, Murray JC, Bulsara MK. Antenatal screening for sexually transmitted infections in remote Australia. Aust N Z J Obstet Gynaecol 2003; 43: 457-462.

©The Medical Journal of Australia 2004 www.mja.com.au ISSN: 0025-729X

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